Polycystic ovary syndrome (PCOS) is a heterogeneous and extremely common disease with
symptoms that vary with the age of the patient, typically characterized by hyperandrogenism …

Life expectancy has been on the rise for the past few decades, but healthy life expectancy
has not kept pace, leading to a global burden of age-associated disorders. Advancing age is …

The systemic immunity-inflammation index (SII) is a novel inflammatory marker, and aberrant
blood lipid levels are linked to inflammation. This study aimed to look at the probable link …

Myocardial ischemia-reperfusion injury (MIRI) results in the aggravation of myocardial injury
caused by rapid recanalization of the ischemic myocardium. In the past few years, there is a …

Obesity is one of the prominent global health issues, contributing to the growing prevalence
of insulin resistance and type 2 diabetes. Chronic inflammation in adipose tissue is …

Atherosclerosis and its clinical manifestations, coronary and cerebral artery diseases, are
the most common cause of death worldwide. The main pathophysiological mechanism for …

Metformin is one of the most widely used drugs for type 2 diabetes and it also exhibits
cardiovascular protective activity. However, the underlying mechanism of its action is not …

Diabetes mellitus is a group of chronic diseases characterized by high blood glucose levels.
Diabetic patients have a higher risk of sustaining osteoporotic fractures than non-diabetic …

Altered mitochondrial function is currently recognized as an important factor in
atherosclerosis initiation and progression. Mitochondrial dysfunction can be caused by …

Metformin has been involved in modulating inflammatory state and inhibiting cell
proliferation and angiogenesis. This study aimed to determine whether metformin alleviates …