From bacteria to humans, cells secrete a large variety of membrane-bound extracellular
vesicles. Only relatively recently has it however started to become clear that the exovesicular …

Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …

Viral nucleic acids often trigger an innate immune response in infected cells. Many viruses,
including hepatitis C virus (HCV), have evolved mechanisms to evade intracellular …

Hepatitis C virus, a major human pathogen, produces infectious virus particles with several
unique features, such as an ability to interact with serum lipoproteins, a dizzyingly …

Hepatitis C virus (HCV) is a major global health burden accounting for around 170 million
chronic infections worldwide. Although highly potent direct-acting antiviral drugs to treat …

The ESCRT machinery consists of the peripheral membrane protein complexes ESCRT-0,-I,-
II,-III, and Vps4–Vta1, and the ALIX homodimer. The ESCRT system is required for …

The deregulation of microRNAs (miRNAs) plays an important role in human
hepatocarcinogenesis. In this study, we highlight exosomes as mediators involved in …

Hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver cirrhosis, and
hepatocellular carcinoma in humans. We showed previously that HCV induces autophagy …

Toxoplasma gondii is a master manipulator capable of effectively siphoning the resources
from the host cell for its intracellular subsistence. However, the molecular underpinnings of …

A key aspect of successful viral vaccine design is the elicitation of neutralizing antibodies
targeting viral attachment and fusion glycoproteins that embellish viral particles. This …