DNA methylation is involved in numerous biological processes and is deregulated in human
diseases. The modulation of the activity of the enzymes and proteins in charge of DNA …

Flaxseeds have been known for their anti-cancerous effects due to the high abundance of
lignans released upon ingestion. The most abundant lignan, secoisolariciresinol diglucoside …

Gastrointestinal (GI) malignancies account for substantial mortality and morbidity worldwide.
They are generally promoted by dysregulated signal transduction and epigenetic pathways …

Studies on tocotrienols have progressively revealed the benefits of these vitamin E isoforms
on human health. Beta-tocotrienol (beta-T3) is known to be less available in nature …

Abstract Background The edible fruit Annona cherimola has previously shown many
nutritional and medicinal properties. The current study evaluates the anti-cancer and anti …

Occurrence of cisplatin-resistance in bladder cancer is frequent and results in disease
progression. Thus, novel therapeutic approaches are a high medical need for patients …

Urtica dioica (UD), commonly known as “stinging nettle”, is a herbaceous flowering plant that
is a widely used agent in traditional medicine worldwide. Several formulations of UD leaf …

Hepatocellular carcinoma (HCC) is a worldwide health issue. Epigenetic alterations play a
crucial role in HCC tumorigenesis. Using epigenetic modulators for HCC treatment confers a …

Colorectal cancer (CRC) is one of the significant threats to public health and the sustainable
healthcare system during urbanization. As the primary method of screening, colonoscopy …

Modifications in the epigenetic landscape have been considered a hallmark of cancer.
Histone deacetylation is one of the crucial epigenetic modulations associated with the …