Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
Abstract 'Reactive oxygen species'(ROS) is a generic term that defines a wide variety of
oxidant molecules with vastly different properties and biological functions that range from …
oxidant molecules with vastly different properties and biological functions that range from …
[HTML][HTML] Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
J Guo, X Huang, L Dou, M Yan, T Shen… - Signal Transduction and …, 2022 - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …
tissue and cell functions and significant increases in the risks of various aging-related …
The role of ROS in tumour development and progression
EC Cheung, KH Vousden - Nature Reviews Cancer, 2022 - nature.com
Eukaryotic cells have developed complex systems to regulate the production and response
to reactive oxygen species (ROS). Different ROS control diverse aspects of cell behaviour …
to reactive oxygen species (ROS). Different ROS control diverse aspects of cell behaviour …
[HTML][HTML] Oxidative stress in human pathology and aging: molecular mechanisms and perspectives
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …
Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives
JS Bhatti, A Sehrawat, J Mishra, IS Sidhu… - Free Radical Biology …, 2022 - Elsevier
Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …
Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy
B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
Oxidative stress: The core pathogenesis and mechanism of Alzheimer's disease
As the number of patients with Alzheimer's disease (AD) increases, it brings great suffering
to their families and causes a heavy socioeconomic burden to society. A vast amount of …
to their families and causes a heavy socioeconomic burden to society. A vast amount of …
A common feature of pesticides: oxidative stress—the role of oxidative stress in pesticide‐induced toxicity
Pesticides are important chemicals or biological agents that deter or kill pests. The use of
pesticides has continued to increase as it is still considered the most effective method to …
pesticides has continued to increase as it is still considered the most effective method to …
[HTML][HTML] Plant hormones and neurotransmitter interactions mediate antioxidant defenses under induced oxidative stress in plants
Due to global climate change, abiotic stresses are affecting plant growth, productivity, and
the quality of cultivated crops. Stressful conditions disrupt physiological activities and …
the quality of cultivated crops. Stressful conditions disrupt physiological activities and …
[HTML][HTML] Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
H Slika, H Mansour, N Wehbe, SA Nasser… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …
species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants …