[HTML][HTML] Tumoricidal activity of human dendritic cells

J Tel, S Anguille, CEJ Waterborg, EL Smits… - Trends in …, 2014 - cell.com
Dendritic cells (DCs) are a family of professional antigen-presenting cells (APCs) that are
able to initiate innate and adaptive immune responses against pathogens and tumor cells …

Molecular classification of thyroid nodules using high-dimensionality genomic data

D Chudova, JI Wilde, ET Wang, H Wang… - The Journal of …, 2010 - academic.oup.com
Objective: We set out to develop a molecular test that distinguishes benign and malignant
thyroid nodules using fine-needle aspirates (FNA). Design: We used mRNA expression …

Molecular markers in thyroid cancer diagnostics

MA Kato, TJ Fahey - Surgical Clinics, 2009 - surgical.theclinics.com
Approximately 37,340 cases of thyroid cancer were projected for 2008 with resultant 1590
deaths, making it the most common endocrine malignancy in the United States. Thyroid …

An empirical assessment of validation practices for molecular classifiers

PJ Castaldi, IJ Dahabreh… - Briefings in …, 2011 - academic.oup.com
Proposed molecular classifiers may be overfit to idiosyncrasies of noisy genomic and
proteomic data. Cross-validation methods are often used to obtain estimates of classification …

[HTML][HTML] The transcription factor ETV5 mediates BRAFV600E-induced proliferation and TWIST1 expression in papillary thyroid cancer cells

OR Puli, BP Danysh, E McBeath, DK Sinha, NM Hoang… - Neoplasia, 2018 - Elsevier
The ETS family of transcription factors is involved in several normal remodeling events and
pathological processes including tumor progression. ETS transcription factors are divided …

[HTML][HTML] Alterations in gene expression of proprotein convertases in human lung cancer have a limited number of scenarios

IV Demidyuk, AV Shubin, EV Gasanov, AM Kurinov… - PLoS …, 2013 - journals.plos.org
Proprotein convertases (PCs) is a protein family which includes nine highly specific subtilisin-
like serine endopeptidases in mammals. The system of PCs is involved in carcinogenesis …

Three-gene molecular diagnostic model for thyroid cancer

NB Prasad, J Kowalski, HL Tsai, K Talbot, H Somervell… - Thyroid, 2012 - liebertpub.com
Background: The preoperative diagnosis of thyroid nodules primarily depends upon fine
needle aspiration (FNA) cytology. However, up to 25% of FNA samples have associated …

Systems and methods for expression-based classification of thyroid tissue

E Davicioni, SM Wiseman - US Patent 9,206,482, 2015 - Google Patents
US9206482B2 - Systems and methods for expression-based classification of thyroid tissue -
Google Patents US9206482B2 - Systems and methods for expression-based classification of …

FN1, GALE, MET, and QPCT overexpression in papillary thyroid carcinoma: Molecular analysis using frozen tissue and routine fine‐needle aspiration biopsy samples

CAT da Silveira Mitteldorf… - Diagnostic …, 2011 - Wiley Online Library
Thyroid nodules are a common clinical problem, and fine‐needle aspiration biopsy (FNAB)
is widely used for its evaluation. Only 5% are malignant, being papillary carcinoma (PC) the …

Cyclin D1 and D3 overexpression predicts malignant behavior in thyroid fine‐needle aspirates suspicious for Hurthle cell neoplasms

G Troncone, M Volante, A Iaccarino… - … : A Journal of the …, 2009 - Wiley Online Library
BACKGROUND: Thyroid fine‐needle aspiration (FNA) samples that feature a follicular‐
patterned, monotonous Hurthle (oncocytic) cell population cannot be diagnosed reliably …