Profound and debilitating fatigue is the most common complaint reported among individuals
with autoimmune disease, such as systemic lupus erythematosus, multiple sclerosis, type 1 …

Mast cells are tissue-resident, innate immune cells that play a key role in the inflammatory
response and tissue homeostasis. Mast cells accumulate in the tumor stroma of different …

Background The COVID-19 pandemic due to SARS-CoV-2 infection can produce Acute
Respiratory Distress Syndrome as a result of a pulmonary cytokine storm. Antihistamines are …

Coronavirus disease 2019 (COVID-19) has quickly become a global pandemic. Reports
from different parts of the world indicate that a significant proportion of people who have …

Histidine is an essential amino acid (EAA) in mammals, fish, and poultry. We aim to give an
overview of the metabolism and physiological effects of histidine in humans and different …

Fermented and/or protein-rich foods, the most widely consumed worldwide, are the most
susceptible to the presence of high levels of biogenic amines (BAs). Many reviews have …

In recent decades, aquaculture has played a significant role in fulfilling the vast demand for
animal protein requirements and consequently in food security. However, environmental …

Most of the anti-inflammatory drugs in clinical practice are becoming outdated owing to their
potential side and adverse effects. These are found to be highly unsafe for long term use …

Tumor cell phenotypes and anti-tumor immune responses are shaped by local metabolite
availability, but intratumoral metabolite heterogeneity (IMH) and its phenotypic …

One of the most powerful and multifaceted cytokines produced by immune cells are type I
interferons (IFNs), the basal secretion of which contributes to the maintenance of immune …