Parkinson's disease (PD) is a neurodegenerative disorder where alpha-synuclein plays a
central role in the death and dysfunction of neurons, both, in central, as well as in the …

Microglia are critical nervous system‐specific immune cells serving as tissue‐resident
macrophages influencing brain development, maintenance of the neural environment …

Parkinson's disease (PD) is a chronic and progressive disorder characterized
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …

The discovery of the central role played by the protein alpha-synuclein in Parkinson's
disease and other Lewy body brain disorders has had a great relevance in the …

Accumulation of alpha-synuclein (α-syn) in the central nervous system (CNS) is a core
feature of Parkinson disease (PD) that leads to activation of the innate immune system …

Immune changes occur in all neurodegenerative conditions, but there are significant
differences between diseases. For Parkinson's disease (PD), the immune system …

Parkinson's Disease (PD) is an age-related, chronic neurodegenerative disorder. At present,
there are no disease-modifying therapies to prevent PD progression. Activated microglia …

Despite extensive effort on studying inflammatory processes in the CNS of Parkinson's
disease (PD) patients, implications of peripheral monocytes are still poorly understood …

The neuropathological hallmarks of Parkinson's disease (PD) are the degeneration and
death of dopamine‐producing neurons in the ventral midbrain, the widespread …

Mounting evidence suggests that neuroinflammation is not just a consequence but a vital
contributor to the development and progression of Parkinson's disease (PD). Microglia in …