DPP-4 inhibitors and type 2 diabetes mellitus in Parkinson's disease: a mutual relationship

M Alrouji, HM Al-Kuraishy, AK Al-Buhadily… - Pharmacological …, 2023 - Springer
Parkinson's disease (PD) usually occurs due to the degeneration of dopaminergic neurons
in the substantia nigra (SN). Management of PD is restricted to symptomatic improvement …

Irisin/PGC-1α/FNDC5 pathway in Parkinson's disease: truth under the throes

NH Ali, NA Alhamdan, HM Al-Kuraishy… - Naunyn-Schmiedeberg's …, 2024 - Springer
Parkinson's disease (PD) is considered one of the most common neurodegenerative brain
diseases which involves the deposition of α-synuclein. Irisin hormone, a newly discovered …

[HTML][HTML] SARS-CoV-2 infection and dysregulation of nuclear factor erythroid-2-related factor 2 (Nrf2) pathway

RS Hamad, HM Al-Kuraishy, A Alexiou… - Cell Stress and …, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a recent pandemic caused by a novel
severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) leading to pulmonary and …

Dantrolene and ryanodine receptors in COVID‐19: The daunting task and neglected warden

L Alkazmi, HM Al‐kuraishy… - Clinical and …, 2023 - Wiley Online Library
Dantrolene (DTN) is a ryanodine receptor (RyR) antagonist that inhibits Ca2+ release from
stores in the sarcoplasmic reticulum. DTN is mainly used in the management of malignant …

The possible role of nuclear factor erythroid‐2‐related factor 2 activators in the management of Covid‐19

HM Al‐kuraishy, AI Al‐Gareeb… - … of Biochemical and …, 2024 - Wiley Online Library
COVID‐19 is caused by a novel SARS‐CoV‐2 leading to pulmonary and extra‐pulmonary
manifestations due to oxidative stress (OS) development and hyperinflammation. COVID‐19 …

In Vivo and in Vitro Mitigation of Salmonella Typhimurium Isolates by Fortunella Japonica Fruit Extract

B Alotaibi, TA El-Masry, WA Negm, A Saleh… - Current …, 2024 - Springer
The vast dissemination of resistance to different antibiotics among bacterial pathogens,
especially foodborne pathogens, has drawn major research attention. Thus, many attempts …

Green synthesised zinc oxide nanoparticles reveal potent in vivo and in vitro antibacterial efficacy against Proteus mirabilis isolates

E Elekhnawy, AS Almurshedi, DH Abdelkader… - International Journal of …, 2023 - Elsevier
Currently, the spread of antimicrobial resistance dissemination is expanding at an
accelerated rate. Therefore, numerous researchers have investigated alternative treatments …

Antibacterial potential of Euphorbia canariensis against Pseudomonas aeruginosa bacteria causing respiratory tract infections

B Alotaibi, E Elekhnawy, TA El-Masry… - Artificial Cells …, 2024 - Taylor & Francis
The widespread dissemination of bacterial resistance has led to great attention being paid to
finding substitutes for traditionally used antibiotics. Plants are rich in various phytochemicals …

Panicum maximum Jacq. mediated green synthesis of silver nanoparticles: synthesis, characterization, and biological activities supported by molecular docking

HW Alhamdi, HK Anazi, FA Mokhtar… - Artificial Cells …, 2024 - Taylor & Francis
This study uses the aerial parts of Panicum maximum total extract (PMTE) to synthesize
silver nanoparticles (AgNPs) in an environmentally friendly manner. TEM, SEM, FTIR, X-ray …

DPP-4 Inhibitors as a savior for COVID-19 patients with diabetes

S Nag, S Mandal, O Mukherjee, S Mukherjee… - Future …, 2023 - Taylor & Francis
Diabetic patients are at particular risk of severe COVID-19. Human dipeptidyl peptidase-4
(DPP-4) is a membrane-bound aminopeptidase that regulates insulin release by inactivating …