Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases
T Sakuragi, S Nagata - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Cellular membranes function as permeability barriers that separate cells from the external
environment or partition cells into distinct compartments. These membranes are lipid …
environment or partition cells into distinct compartments. These membranes are lipid …
Macrophages: the good, the bad, and the gluttony
Macrophages are dynamic cells that play critical roles in the induction and resolution of
sterile inflammation. In this review, we will compile and interpret recent findings on the …
sterile inflammation. In this review, we will compile and interpret recent findings on the …
[HTML][HTML] Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption
Osteoclasts are large multinucleated bone-resorbing cells formed by the fusion of monocyte/
macrophage-derived precursors that are thought to undergo apoptosis once resorption is …
macrophage-derived precursors that are thought to undergo apoptosis once resorption is …
Novel insights into macrophage diversity in rheumatoid arthritis synovium
MA Boutet, G Courties, A Nerviani, B Le Goff… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease affecting joints and
causing progressive damage and disability. Macrophages are of critical importance in the …
causing progressive damage and disability. Macrophages are of critical importance in the …
Sequential activation of heterogeneous macrophage phenotypes is essential for biomaterials-induced bone regeneration
Macrophage has been gradually recognized as a central regulator in tissue regeneration,
and the study of how macrophage mediates biomaterials-induced bone regeneration …
and the study of how macrophage mediates biomaterials-induced bone regeneration …
Phosphatidylserine liposome multilayers mediate the M1-to-M2 macrophage polarization to enhance bone tissue regeneration
An appropriate immune microenvironment, governed by macrophages, is essential for rapid
tissue regeneration after biomaterial implantation. The macrophage phenotypes, M1 …
tissue regeneration after biomaterial implantation. The macrophage phenotypes, M1 …
Influence of the TGF-β superfamily on osteoclasts/osteoblasts balance in physiological and pathological bone conditions
J Jann, S Gascon, S Roux, N Faucheux - International journal of …, 2020 - mdpi.com
The balance between bone forming cells (osteoblasts/osteocytes) and bone resorbing cells
(osteoclasts) plays a crucial role in tissue homeostasis and bone repair. Several hormones …
(osteoclasts) plays a crucial role in tissue homeostasis and bone repair. Several hormones …
Multinucleated giant cells: current insights in phenotype, biological activities, and mechanism of formation
K Ahmadzadeh, M Vanoppen, CD Rose… - Frontiers in cell and …, 2022 - frontiersin.org
Monocytes and macrophages are innate immune cells with diverse functions ranging from
phagocytosis of microorganisms to forming a bridge with the adaptive immune system. A …
phagocytosis of microorganisms to forming a bridge with the adaptive immune system. A …
Flagging fusion: Phosphatidylserine signaling in cell–cell fusion
JM Whitlock, LV Chernomordik - Journal of Biological Chemistry, 2021 - ASBMB
Formations of myofibers, osteoclasts, syncytiotrophoblasts, and fertilized zygotes share a
common step, cell–cell fusion. Recent years have brought about considerable progress in …
common step, cell–cell fusion. Recent years have brought about considerable progress in …
[PDF][PDF] Pharmacological agents and natural compounds: available treatments for osteoporosis.
M Martiniakova, M Babikova, R Omelka - Journal of Physiology & …, 2020 - jpp.krakow.pl
Osteoporosis, a systemic skeletal disease characterized by a decrease in bone mass and
deterioration of bone structure leading to an increased risk of fragility fractures, represents …
deterioration of bone structure leading to an increased risk of fragility fractures, represents …