The platelet lifeline to cancer: challenges and opportunities
M Haemmerle, RL Stone, DG Menter… - Cancer cell, 2018 - cell.com
Besides their function in limiting blood loss and promoting wound healing, experimental
evidence has highlighted platelets as active players in all steps of tumorigenesis including …
evidence has highlighted platelets as active players in all steps of tumorigenesis including …
Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled …
PM Rothwell, JF Price, FGR Fowkes, A Zanchetti… - The Lancet, 2012 - thelancet.com
Background Daily aspirin reduces the long-term risk of death due to cancer. However, the
short-term effect is less certain, especially in women, effects on cancer incidence are largely …
short-term effect is less certain, especially in women, effects on cancer incidence are largely …
Effect of celecoxib vs placebo added to standard adjuvant therapy on disease-free survival among patients with stage III colon cancer: the CALGB/SWOG 80702 …
JA Meyerhardt, Q Shi, CS Fuchs, J Meyer… - Jama, 2021 - jamanetwork.com
Importance Aspirin and cyclooxygenase 2 (COX-2) inhibitors have been associated with a
reduced risk of colorectal polyps and cancer in observational and randomized studies. The …
reduced risk of colorectal polyps and cancer in observational and randomized studies. The …
Aspirin in the chemoprevention of colorectal neoplasia: an overview
Considerable evidence supports the effectiveness of aspirin for chemoprevention of
colorectal cancer (CRC) in addition to its well-established benefits in the prevention of …
colorectal cancer (CRC) in addition to its well-established benefits in the prevention of …
[HTML][HTML] Aspirin in the treatment of cancer: reductions in metastatic spread and in mortality: a systematic review and meta-analyses of published studies
PC Elwood, G Morgan, JE Pickering, J Galante… - PloS one, 2016 - journals.plos.org
Background Low-dose aspirin has been shown to reduce the incidence of cancer, but its
role in the treatment of cancer is uncertain. Objectives We conducted a systematic search of …
role in the treatment of cancer is uncertain. Objectives We conducted a systematic search of …
Aspirin use after diagnosis but not prediagnosis improves established colorectal cancer survival: a meta-analysis
P Li, H Wu, H Zhang, Y Shi, J Xu, Y Ye, D Xia, J Yang… - Gut, 2015 - gut.bmj.com
Objective The objective of this meta-analysis was to systematically assess the survival
benefit of aspirin use before or after diagnosis for patients with colorectal cancer (CRC) …
benefit of aspirin use before or after diagnosis for patients with colorectal cancer (CRC) …
Use of aspirin postdiagnosis improves survival for colon cancer patients
E Bastiaannet, K Sampieri, OM Dekkers… - British journal of …, 2012 - nature.com
Background: The preventive role of non-steroid anti-inflammatory drugs (NSAIDs) and
aspirin, in particular, on colorectal cancer is well established. More recently, it has been …
aspirin, in particular, on colorectal cancer is well established. More recently, it has been …
Aspirin for the prevention of colorectal cancer
X Garcia-Albeniz, AT Chan - Best practice & research Clinical …, 2011 - Elsevier
Over 600,000 people worldwide die of colorectal cancer (CRC) annually, highlighting the
importance of developing effective prevention strategies. Among proposed chemopreventive …
importance of developing effective prevention strategies. Among proposed chemopreventive …
Aspirin and COX-2 inhibitor use in patients with stage III colon cancer
K Ng, JA Meyerhardt, AT Chan, K Sato… - Journal of the …, 2015 - academic.oup.com
We conducted a prospective, observational study of aspirin and COX-2 inhibitor use and
survival in stage III colon cancer patients enrolled in an adjuvant chemotherapy trial. Among …
survival in stage III colon cancer patients enrolled in an adjuvant chemotherapy trial. Among …
Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology
Regular use of aspirin reduces incidence and mortality of various cancers, including
colorectal cancer. Anticancer effect of aspirin represents one of the 'Provocative Questions' …
colorectal cancer. Anticancer effect of aspirin represents one of the 'Provocative Questions' …