Influenza A virus cell entry, replication, virion assembly and movement

D Dou, R Revol, H Östbye, H Wang… - Frontiers in …, 2018 - frontiersin.org
Influenza viruses replicate within the nucleus of the host cell. This uncommon RNA virus trait
provides influenza with the advantage of access to the nuclear machinery during replication …

Viral pandemics of the last four decades: pathophysiology, health impacts and perspectives

S Roychoudhury, A Das, P Sengupta, S Dutta… - International journal of …, 2020 - mdpi.com
The last four decades has witnessed some of the deadliest viral pandemics with far-reaching
consequences. These include the Human Immunodeficiency Virus (HIV)(1981), Severe …

[HTML][HTML] Impact of lipid nanoparticle size on mRNA vaccine immunogenicity

KJ Hassett, J Higgins, A Woods, B Levy, Y Xia… - Journal of Controlled …, 2021 - Elsevier
Lipid nanoparticles (LNP) are effective delivery vehicles for messenger RNA (mRNA) and
have shown promise for vaccine applications. Yet there are no published reports detailing …

The mechanism behind influenza virus cytokine storm

Y Gu, X Zuo, S Zhang, Z Ouyang, S Jiang, F Wang… - Viruses, 2021 - mdpi.com
Influenza viruses are still a serious threat to human health. Cytokines are essential for cell-to-
cell communication and viral clearance in the immune system, but excessive cytokines can …

A review of progress in single particle tracking: from methods to biophysical insights

C Manzo, MF Garcia-Parajo - Reports on progress in physics, 2015 - iopscience.iop.org
Optical microscopy has for centuries been a key tool to study living cells with minimum
invasiveness. The advent of single molecule techniques over the past two decades has …

Single-virus tracking: from imaging methodologies to virological applications

SL Liu, ZG Wang, HY Xie, AA Liu, DC Lamb… - Chemical …, 2020 - ACS Publications
Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

Influenza virus-induced lung injury: pathogenesis and implications for treatment

S Herold, C Becker, KM Ridge… - European Respiratory …, 2015 - Eur Respiratory Soc
The influenza viruses are some of the most important human pathogens, causing substantial
seasonal and pandemic morbidity and mortality. In humans, infection of the lower respiratory …

Characterization of lipid–protein interactions and lipid-mediated modulation of membrane protein function through molecular simulation

MP Muller, T Jiang, C Sun, M Lihan, S Pant… - Chemical …, 2019 - ACS Publications
The cellular membrane constitutes one of the most fundamental compartments of a living
cell, where key processes such as selective transport of material and exchange of …

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

HT McMahon, E Boucrot - Nature reviews Molecular cell biology, 2011 - nature.com
Clathrin-mediated endocytosis is the endocytic portal into cells through which cargo is
packaged into vesicles with the aid of a clathrin coat. It is fundamental to neurotransmission …

Mechanisms of endocytosis

GJ Doherty, HT McMahon - Annual review of biochemistry, 2009 - annualreviews.org
Endocytic mechanisms control the lipid and protein composition of the plasma membrane,
thereby regulating how cells interact with their environments. Here, we review what is known …