Conjugated ynones in organic synthesis

C Nájera, LK Sydnes, M Yus - Chemical Reviews, 2019 - ACS Publications
This review article will consider the preparation and application of ynones in synthetic
organic chemistry. Concerning the preparation of these bifunctional compounds, several …

An insight into the advanced synthetic recipes to access ubiquitous indole heterocycles

BS Mathada, NG Yernale, JN Basha, J Badiger - Tetrahedron Letters, 2021 - Elsevier
Indoles are amongst the most essential class of heteroaromatics in organic chemistry, being
commonly found in biologically active natural products. Indole and its derivatives have …

Visible-light-induced intramolecular charge transfer in the radical spirocyclisation of indole-tethered ynones

HE Ho, A Pagano, JA Rossi-Ashton, JR Donald… - Chemical …, 2020 - pubs.rsc.org
Indole-tethered ynones form an intramolecular electron donor–acceptor complex that can
undergo visible-light-induced charge transfer to promote thiyl radical generation from thiols …

Recent Advances in Indole Synthesis and the Related Alkylation

J Ma, R Feng, ZB Dong - Asian Journal of Organic Chemistry, 2023 - Wiley Online Library
The derivatives of indoles are very useful intermediates in pharmaceuticals and organic
synthesis. The efficient synthesis of the indole blocks and related functionalizations …

Indole-ynones as privileged substrates for radical dearomatizing spirocyclization cascades

N Inprung, HE Ho, JA Rossi-Ashton, RG Epton… - Organic …, 2022 - ACS Publications
Indole-ynones have been established as general substrates for radical dearomatizing
spirocyclization cascade reactions. Five distinct and varied synthetic protocols have been …

Synthesis of functionalized indoles via cascade benzannulation strategies: a decade's overview

S Sahu, A Banerjee, S Kundu… - Organic & …, 2022 - pubs.rsc.org
Indoles are one of the most prominent aromatic heterocycles in the organic chemistry field.
Due to their widespread presence in various natural products, alkaloids, drugs, approved …

Rhodium-Catalyzed Coordination-Assisted Regioselective and Migratory Three-Point Double Annulation of o-Alkenyl Phenols with Tertiary Propargyl Alcohols

A Nagireddy, R Kotipalli, JB Nanubolu… - Organic …, 2022 - ACS Publications
We disclose herein a Rh (III)-catalyzed migratory three-point double annulation of o-alkenyl
phenols with propargyl alcohols for de novo construction of naphtho furan derivatives in a …

Recent Advances in Silver‐Catalyzed Transformations of Electronically Unbiased Alkenes and Alkynes

M Li, W Wu, H Jiang - ChemCatChem, 2020 - Wiley Online Library
Silver, as one of the most ancient coinage metals, has attracted a plethora of attention from
chemists in recent years due to the easy availability, high catalytic efficiency and multiple …

Merging π-Acid and Pd Catalysis: Dearomatizing Spirocyclization/Cross-Coupling Cascade Reactions of Alkyne-Tethered Aromatics

HE Ho, TC Stephens, TJ Payne, P O'Brien… - ACS …, 2018 - ACS Publications
A one-pot protocol for the dearomatizing spirocyclization/cross-coupling of alkyne-tethered
indoles/pyrroles is described. Mechanistic studies support a process by which palladium …

Indole synthesis using silver catalysis

AK Clarke, HE Ho, JA Rossi‐Ashton… - Chemistry–An Asian …, 2019 - Wiley Online Library
Indoles are amongst the most important classes of heteroaromatics in organic chemistry,
commonly found in biologically active natural products and therapeutically useful …