Selection balancing at innate immune genes: Adaptive polymorphism maintenance in toll-like receptors

P Minias, M Vinkler - Molecular Biology and Evolution, 2022 - academic.oup.com
Balancing selection is a classic mechanism for maintaining variability in immune genes
involved in host–pathogen interactions. However, it remains unclear how widespread the …

Natural selection directing molecular evolution in vertebrate viral sensors

B Melepat, T Li, M Vinkler - Developmental & Comparative Immunology, 2024 - Elsevier
Diseases caused by pathogens contribute to molecular adaptations in host immunity. Variety
of viral pathogens challenging animal immunity can drive positive selection diversifying …

Leveraging an existing whole‐genome resequencing population data set to characterize toll‐like receptor gene diversity in a threatened bird

M Magid, JR Wold, R Moraga… - Molecular Ecology …, 2022 - Wiley Online Library
Species recovery programs are increasingly using genomic data to measure neutral genetic
diversity and calculate metrics like relatedness. While these measures can inform …

Differences between mates at the TLR1Lb locus are associated with lower reproductive success in a long-lived seabird

M Gousy-Leblanc, T Merkling, L Colston-Nepali… - Scientific Reports, 2024 - nature.com
Genetic diversity can influence fitness components such as survival and reproductive
success. Yet the association between genetic diversity and fitness based on neutral loci is …

Functional immunogenetic variation, rather than local adaptation, predicts ectoparasite infection intensity in a model fish species

KP Phillips, J Cable, RS Mohammed… - Molecular …, 2021 - Wiley Online Library
Natural host populations differ in their susceptibility to infection by parasites, and these
intrapopulation differences are still an incompletely understood component of host‐parasite …

Beyond neutral loci: Examining immune gene variation in tigers (Panthera tigris)

BV Aditi, U Ramakrishnan - bioRxiv, 2024 - biorxiv.org
Isolated and inbred populations are at a higher risk to extinction due to the loss of genetic
diversity. Carnivores are particularly susceptible to isolation due to their ecological …

The correspondence between genotype at bacterial and viral-facing Toll-like receptors and preen oil chemical composition in song sparrows

J To - 2024 - ir.lib.uwo.ca
Mate choice can optimize immune genotypes of offspring and thus reinforce parasite-
mediated selection on immune genes. Information about genotype at class II major …

Comment on: Assessment of the dunnocks' introduction to New Zealand using innate immune-gene diversity, by Lara et al

P Pavel - Evolutionary Ecology, 2021 - Springer
In a correction (Lara et al. 2021) to a recent study on the immune-gene diversity of
introduced population of dunnocks (Lara et al. 2020) the authors state that in 1868, 98 …