Thyroid dysfunction and diabetes mellitus are closely linked. Several studies have
documented the increased prevalence of thyroid disorders in patients with diabetes mellitus …

The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …

Non-alcoholic fatty liver disease (NAFLD) is an increasingly common condition, strongly
associated with the metabolic syndrome, that can lead to progressive hepatic fibrosis …

Both environmental and genetic triggers factor into the etiology of autoimmune thyroid
disease (AITD), including Graves' disease (GD) and Hashimoto's thyroiditis (HT). Although …

Protein tyrosine phosphorylation is a key regulatory process in virtually all aspects of cellular
functions. Dysregulation of protein tyrosine phosphorylation is a major cause of human …

Background Multiple sclerosis has a clinically significant heritable component. We
conducted a genomewide association study to identify alleles associated with the risk of …

Genetic susceptibility to type 1 diabetes (T1D) has been a subject of intensive study for
nearly four decades. This article will present the history of these studies, beginning with …

Genome-wide strategies have driven the discovery of more than 300 susceptibility loci for
autoimmune diseases. However, for almost all loci, understanding of the mechanisms …

Recent advances in our understanding of genetic-epigenetic interactions have unraveled
new mechanisms underlying the etiology of complex autoimmune diseases. Autoimmune …

Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's
thyroiditis (HT) are prevalent autoimmune diseases, affecting up to 5% of the general …