Chlamydomonas reinhardtii: A Factory of Nutraceutical and Food Supplements for Human Health

A Masi, F Leonelli, V Scognamiglio, G Gasperuzzo… - Molecules, 2023 - mdpi.com
Chlamydomonas reinhardtii (C. reinhardtii) is one of the most well-studied microalgae
organisms that revealed important information for the photosynthetic and metabolic …

Selectable Markers and Reporter Genes for Engineering the Chloroplast of Chlamydomonas reinhardtii

L Esland, M Larrea-Alvarez, S Purton - Biology, 2018 - mdpi.com
Chlamydomonas reinhardtii is a model alga of increasing interest as a cell factory for the
production of valuable compounds, including therapeutic proteins and bioactive metabolites …

An RNA thermometer in the chloroplast genome of Chlamydomonas facilitates temperature-controlled gene expression

KP Chung, FV Loiacono, J Neupert, M Wu… - Nucleic Acids …, 2023 - academic.oup.com
Riboregulators such as riboswitches and RNA thermometers provide simple, protein-
independent tools to control gene expression at the post-transcriptional level. In bacteria …

New tools for chloroplast genetic engineering allow the synthesis of human growth hormone in the green alga Chlamydomonas reinhardtii

T Wannathong, JC Waterhouse, REB Young… - Applied microbiology …, 2016 - Springer
In recent years, there has been an increasing interest in the exploitation of microalgae in
industrial biotechnology. Potentially, these phototrophic eukaryotes could be used for the …

Cloning and expression of an anti-cancerous cytokine: human IL-29 gene in Chlamydomonas reinhardtii

M Akram, MA Khan, N Ahmed, R Bhatti, R Pervaiz… - AMB Express, 2023 - Springer
Green algae, Chlamydomonas reinhardtii, with low cultivation cost, absence of endotoxins
and insusceptibility to human pathogens is emerging as a potential system for the future …

Harnessing the algal chloroplast for heterologous protein production

EA Cutolo, G Mandalà, L Dall'Osto, R Bassi - Microorganisms, 2022 - mdpi.com
Photosynthetic microbes are gaining increasing attention as heterologous hosts for the light-
driven, low-cost production of high-value recombinant proteins. Recent advances in the …

Environmental and nuclear influences on microalgal chloroplast gene expression

SE Carrera-Pacheco, B Hankamer, M Oey - Trends in Plant Science, 2023 - cell.com
Microalgal chloroplasts, such as those of the model organism Chlamydomonas reinhardtii,
are emerging as a new platform to produce recombinant proteins, including industrial …

Cell death patterns due to warm ischemia or reperfusion in renal tubular epithelial cells originating from human, mouse, or the native hibernator hamster

T Eleftheriadis, G Pissas, G Antoniadi, V Liakopoulos… - Biology, 2018 - mdpi.com
Ischemia–reperfusion injury contributes to the pathogenesis of many diseases, with acute
kidney injury included. Hibernating mammals survive prolonged bouts of deep torpor with a …

Manipulation of the microalgal chloroplast by genetic engineering for biotechnological utilization as a green biofactory

YM Kwon, KW Kim, TY Choi, SY Kim… - World Journal of …, 2018 - Springer
The chloroplast is an essential organelle in microalgae for conducting photosynthesis, thus
enabling the photoautotrophic growth of microalgae. In addition to photosynthesis, the …

Optimising light conditions increases recombinant protein production in Chlamydomonas reinhardtii chloroplasts

SEC Pacheco, B Hankamer, M Oey - Algal research, 2018 - Elsevier
The green alga Chlamydomonas reinhardtii provides a platform for cheap, scalable and safe
production of complex proteins. Despite the fact that chloroplast gene expression in …