Keystone taxa as drivers of microbiome structure and functioning

S Banerjee, K Schlaeppi… - Nature Reviews …, 2018 - nature.com
Microorganisms have a pivotal role in the functioning of ecosystems. Recent studies have
shown that microbial communities harbour keystone taxa, which drive community …

Human gut microbiota and gastrointestinal cancer

C Meng, C Bai, TD Brown, LE Hood… - Genomics, Proteomics …, 2018 - academic.oup.com
Human gut microbiota play an essential role in both healthy and diseased states of humans.
In the past decade, the interactions between microorganisms and tumors have attracted …

The gut–lung axis in respiratory disease

BJ Marsland, A Trompette… - Annals of the American …, 2015 - atsjournals.org
Host–microorganism interactions shape local cell functionality, immune responses, and can
influence disease development. Evidence indicates that the impact of host–microbe …

The human microbiome: at the interface of health and disease

I Cho, MJ Blaser - Nature Reviews Genetics, 2012 - nature.com
Interest in the role of the microbiome in human health has burgeoned over the past decade
with the advent of new technologies for interrogating complex microbial communities. The …

Host–microorganism interactions in lung diseases

BJ Marsland, ES Gollwitzer - Nature Reviews Immunology, 2014 - nature.com
Until recently, the airways were thought to be sterile unless infected; however, a shift
towards molecular methods for the quantification and sequencing of bacterial DNA has …

The human gastric microbiota: Is it time to rethink the pathogenesis of stomach diseases?

G Nardone, D Compare - United European gastroenterology …, 2015 - journals.sagepub.com
Introduction Although long thought to be a sterile organ, due to its acid production, the
human stomach holds a core microbiome. Aim To provide an update of findings related to …

Gastrointestinal malignancy and the microbiome

MT Abreu, RM Peek Jr - Gastroenterology, 2014 - Elsevier
Microbial species participate in the genesis of a substantial number of malignancies—in
conservative estimates, at least 15% of all cancer cases are attributable to infectious agents …

Microbiota, disease, and back to health: a metastable journey

R Blumberg, F Powrie - Science translational medicine, 2012 - science.org
Alterations in the composition of the commensal microbiota have been observed in many
complex diseases. Understanding the basis for these changes, how they relate to disease …

The active bacterial assemblages of the upper GI tract in individuals with and without Helicobacter infection

C Schulz, K Schütte, N Koch, R Vilchez-Vargas… - Gut, 2018 - gut.bmj.com
Objective Patients infected with Helicobacter pylori develop chronic gastritis with a subgroup
progressing to further complications. The role of microbiota from the oral cavity swallowed …

Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori …

K Lertpiriyapong, MT Whary, S Muthupalani, JL Lofgren… - Gut, 2014 - gut.bmj.com
Objectives Gastric colonisation with intestinal flora (IF) has been shown to promote
Helicobacter pylori (Hp)-associated gastric cancer. However, it is unknown if the mechanism …