Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion
formation methods and to preserve the stability of carriers in liquid media. The deposition of …

The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …

Inflammation, a common feature of many diseases, is an essential immune response that
enables survival and maintains tissue homeostasis. However, in some conditions, the …

Abstract Background and Aims Oral drug delivery is the most attractive pathway for
ulcerative colitis [UC] therapy, since it has many advantages. However, this strategy has …

Oral colon-specific delivery systems emerged as the main therapeutic cargos by making a
significant impact in the field of modern medicine for local drug delivery in intestinal …

The complex pathogenesis of inflammatory bowel disease (IBD) explains the several
hurdles for finding an efficient approach to cure it. Nowadays, therapeutic protocols aim to …

Methotrexate (MTX) is the first line agent for therapy against rheumatoid arthritis (RA);
however, orally its efficacy is hampered by poor solubility, less permeability, short plasma …

Delivering drugs directly to the inflamed intestinal sites to treat inflammatory bowel disease
(IBD), particularly Crohn's and ulcerative colitis, is highly challenging. Recent advances in …

Intestinal organoids can be used as an ex vivo epithelial model to study different drug
delivery effects on epithelial cells' luminal surface. In this study, the impact of surface charge …