Phage therapy: the pharmacology of antibacterial viruses
K Danis-Wlodarczyk, K Dąbrowska… - Current issues in …, 2021 - mdpi.com
Pharmacology can be differentiated into two key aspects, pharmacodynamics and
pharmacokinetics. Pharmacodynamics describes a drug's impact on the body while …
pharmacokinetics. Pharmacodynamics describes a drug's impact on the body while …
Ecology and evolutionary biology of hindering phage therapy: The phage tolerance vs. phage resistance of bacterial biofilms
ST Abedon - Antibiotics, 2023 - mdpi.com
As with antibiotics, we can differentiate various acquired mechanisms of bacteria-mediated
inhibition of the action of bacterial viruses (phages or bacteriophages) into ones of tolerance …
inhibition of the action of bacterial viruses (phages or bacteriophages) into ones of tolerance …
Phage cocktail development for bacteriophage therapy: toward improving spectrum of activity breadth and depth
Phage therapy is the use of bacterial viruses as antibacterial agents. A primary
consideration for commercial development of phages for phage therapy is the number of …
consideration for commercial development of phages for phage therapy is the number of …
Microbial arsenal of antiviral defenses–part I
AB Isaev, OS Musharova, KV Severinov - Biochemistry (Moscow), 2021 - Springer
Bacteriophages or phages are viruses that infect bacterial cells (for the scope of this review
we will also consider viruses that infect Archaea). Constant threat of phage infection is a …
we will also consider viruses that infect Archaea). Constant threat of phage infection is a …
An optimized checkerboard method for phage-antibiotic synergy detection
I Nikolic, D Vukovic, D Gavric, J Cvetanovic… - Viruses, 2022 - mdpi.com
Phage-antibiotic synergy is a promising therapeutic strategy, but there is no reliable method
for synergism estimation. Although the time-kill curve assay is a gold standard, the method is …
for synergism estimation. Although the time-kill curve assay is a gold standard, the method is …
Overcoming challenges to make bacteriophage therapy standard clinical treatment practice for cystic fibrosis
Individuals with cystic fibrosis (CF) are given antimicrobials as prophylaxis against bacterial
lung infection, which contributes to the growing emergence of multidrug resistant (MDR) …
lung infection, which contributes to the growing emergence of multidrug resistant (MDR) …
Phage-phage, phage-bacteria, and phage-environment communication
ST Abedon - Biocommunication of phages, 2020 - Springer
Besides obtaining and utilizing resources, organisms have three basic ecological tasks: to
survive, to reproduce, and to move. Survival is necessary for reproduction, reproduction …
survive, to reproduce, and to move. Survival is necessary for reproduction, reproduction …
Optimizing Protein Production in Therapeutic Phages against a Bacterial Pathogen, Mycobacterium abscessus
X Xia - Drugs and Drug Candidates, 2023 - mdpi.com
Therapeutic phages against pathogenic bacteria should kill the bacteria efficiently before the
latter evolve resistance against the phages. While many factors contribute to phage …
latter evolve resistance against the phages. While many factors contribute to phage …
Antibacterial Potential of Non-Tailed Icosahedral Phages Alone and in Combination with Antibiotics
D Vukovic, S Gostimirovic, J Cvetanovic, D Gavric… - Current …, 2024 - Springer
Non-tailed icosahedral phages belonging to families Fiersviridae (phages MS2 and Qbeta),
Tectiviridae (PRD1) and Microviridae (phiX174) have not been considered in detail so far as …
Tectiviridae (PRD1) and Microviridae (phiX174) have not been considered in detail so far as …
[HTML][HTML] THE IMPACTS OF PHAGE-ACTINOBACTERIAL INTERACTIONS ON THE ECOLOGICAL FUNCTIONS OF ACTINOBACTERIA
A century ago, the knowledge of phages' contributions in the ecology of Actinobacteria by
controlling its population through lysis was brought to light. Ever since then, scientists have …
controlling its population through lysis was brought to light. Ever since then, scientists have …