The POU domain family of transcription factors regulates developmental processes ranging
from specification of the early embryo to terminal differentiation. About half of these factors …

Although present at relatively low number in the testis, spermatogonial stem cells (SSCs) are
crucial for the establishment and maintenance of spermatogenesis in eukaryotes and, until …

After fertilization, maternal factors direct development and trigger zygotic genome activation
(ZGA) at the maternal-to-zygotic transition (MZT). In zebrafish, ZGA is required for …

The development of multicellular animals is initially controlled by maternal gene products
deposited in the oocyte. During the maternal-to-zygotic transition, transcription of zygotic …

In embryonic stem (ES) cells and in early mouse embryos, the transcription factor Oct4 is an
essential regulator of pluripotency. Oct4 transcriptional targets have been described in ES …

The POU genes represent a diverse class of animal-specific transcription factors that play
important roles in neurogenesis, pluripotency, and cell-type specification. Although previous …

In association with in vitro culture and transplantation, isolation of spermatogonial stem cells
(SSCs) is an excellent approach for investigating spermatogonial physiology in vertebrates …

With the enhancement of commercial manifestation of silver nanoparticles, concerned has
risen on their accumulation in aquatic system and consequent effects on fish development …

Background Pluripotency is a fundamental property of early mammalian development but it
is currently unclear to what extent its cellular mechanisms are conserved in vertebrates or …

POUV is a relatively newly emerged class of POU transcription factors present in jawed
vertebrates (Gnathostomata). The function of POUV-class proteins is inextricably linked to …