Genetic influence on treatment response in psoriasis: new insights into personalized medicine

E Berna-Rico, J Perez-Bootello… - International Journal of …, 2023 - mdpi.com
Psoriasis is a chronic inflammatory disease with an established genetic background. The
HLA-Cw* 06 allele and different polymorphisms in genes involved in inflammatory …

Towards personalized medicine in psoriasis: current progress

E Camela, L Potestio, A Ruggiero… - … : Targets and Therapy, 2022 - Taylor & Francis
Although innovative targeted therapies have positively revolutionized psoriasis treatment
shifting treatment goals to complete or almost complete skin clearance, primary or …

Allelic Variants of HLA-C Upstream Region, PSORS1C3, MICA, TNFA and Genes Involved in Epidermal Homeostasis and Barrier Function Influence the Clinical …

M Morelli, M Galluzzo, C Scarponi, S Madonna… - Vaccines, 2022 - mdpi.com
Several biologic therapies have been developed to treat moderate-to-severe psoriasis, with
patients exhibiting different clinical benefits, possibly due to the heterogeneity of pathogenic …

Pharmaco-omics in psoriasis: paving the way towards personalized medicine

C Antonatos, P Asmenoudi, M Panoutsopoulou… - International Journal of …, 2023 - mdpi.com
The emergence of high-throughput approaches has had a profound impact on personalized
medicine, evolving the identification of inheritable variation to trajectory analyses of transient …

Psoriatic arthritis: development, detection and prevention: a scoping review

A Kimak, E Robak, J Makowska… - Journal of Clinical …, 2023 - mdpi.com
Psoriatic arthritis is a heterogenous chronic inflammatory disease that develops over time in
some patients with psoriasis. The course of the disease is variable, with a broad clinical …

The Role of Genetics on Psoriasis Susceptibility, Comorbidities, and Treatment Response

A Bui, F Orcales, A Kranyak, BY Chung… - Dermatologic …, 2024 - derm.theclinics.com
Psoriasis is a systemic immune-mediated chronic inflammatory disease characterized by
erythematous and scaly skin plaques affecting 3.2% of adults in the United States and up to …

From Manifestations to Innovations: A Deep Dive into Psoriasis, its Clinical Diversity, Conventional Treatments, and Emerging Therapeutic Paradigms

S Garg, M Dixit, I Malhotra, M Singh, V Singh - International …, 2024 - Elsevier
Psoriasis, a persistent inflammatory dermatological illness, places a significant load on
those affected, requiring ongoing investigation into innovative therapies. This review …

Genome‑wide association study and polygenic risk scores predict psoriasis and its shared phenotypes in Taiwan

JS Yang, TY Liu, HF Lu, SC Tsai… - Molecular …, 2024 - spandidos-publications.com
Psoriasis is a chronic inflammatory dermatological disease, and there is a lack of
understanding of the genetic factors involved in psoriasis in Taiwan. To establish …

Pharmacogenetics of psoriasis: predictors of the efficacy of anticytokine biological therapy

EA Shatokhina, IG Egoshina… - Russian Journal of …, 2024 - journals.rcsi.science
Psoriasis is a common chronic immune-mediated inflammatory inflammatory skin disease.
The systemic nature of the inflammatory process, as well as the association with other …

IDENTIFIKASI GEN YANG BERISIKO UNTUK PSORIASIS VULGARIS MELALUI PEMANFAATAN INFORMASI GENOMIC

L Niarisessa, AN Puspitaningrum… - … Sains: Jurnal Ilmiah …, 2023 - ojs.ummada.ac.id
Psoriasis vulgaris merupakan penyakit yang berkaitan dengan autoimun menyebabkan
terjadinya inflamasi pada permukaan kulit. Psoriasis vulgaris ditandai dengan adanya plak …