Cerebral small vessel disease: from a focal to a global perspective
A Ter Telgte, EMC Van Leijsen, K Wiegertjes… - Nature Reviews …, 2018 - nature.com
Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …
Vascular cognitive impairment
M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …
Longitudinal associations of blood phosphorylated Tau181 and neurofilament light chain with neurodegeneration in Alzheimer disease
Importance Plasma phosphorylated tau at threonine 181 (p-tau181) has been proposed as
an easily accessible biomarker for the detection of Alzheimer disease (AD) pathology, but its …
an easily accessible biomarker for the detection of Alzheimer disease (AD) pathology, but its …
Prevention of stroke in patients with silent cerebrovascular disease: a scientific statement for healthcare professionals from the American Heart Association/American …
Two decades of epidemiological research shows that silent cerebrovascular disease is
common and is associated with future risk for stroke and dementia. It is the most common …
common and is associated with future risk for stroke and dementia. It is the most common …
Brain arteriolosclerosis
Abstract Brain arteriolosclerosis (B-ASC), characterized by pathologic arteriolar wall
thickening, is a common finding at autopsy in aged persons and is associated with cognitive …
thickening, is a common finding at autopsy in aged persons and is associated with cognitive …
White matter hyperintensities and imaging patterns of brain ageing in the general population
White matter hyperintensities are associated with increased risk of dementia and cognitive
decline. The current study investigates the relationship between white matter …
decline. The current study investigates the relationship between white matter …
Role of gait speed and grip strength in predicting 10-year cognitive decline among community-dwelling older people
MY Chou, Y Nishita, T Nakagawa, C Tange, M Tomida… - BMC geriatrics, 2019 - Springer
Background The gait speed and handgrip strength represented the core determinants of
physical frailty and sarcopenia, which were reported to be associated with cognitive …
physical frailty and sarcopenia, which were reported to be associated with cognitive …
Clinical presentations and epidemiology of vascular dementia
EE Smith - Clinical Science, 2017 - portlandpress.com
Cerebrovascular and cardiovascular diseases cause vascular brain injury that can lead to
vascular cognitive impairment (VCI). VCI is the second most common neuropathology of …
vascular cognitive impairment (VCI). VCI is the second most common neuropathology of …
White matter hyperintensities across the adult lifespan: relation to age, Aβ load, and cognition
A Garnier-Crussard, S Bougacha, M Wirth… - Alzheimer's research & …, 2020 - Springer
Background White matter hyperintensities (WMH) are very frequent in older adults and
associated with worse cognitive performance. Little is known about the links between WMH …
associated with worse cognitive performance. Little is known about the links between WMH …
The multifactorial nature of healthy brain ageing: Brain changes, functional decline and protective factors
As the global population faces a progressive shift towards a higher median age,
understanding the mechanisms underlying healthy brain ageing has become of paramount …
understanding the mechanisms underlying healthy brain ageing has become of paramount …