Voltage-gated ion channels (VGICs), including those for Na+, Ca2+ and K+, selectively
permeate ions across the cell membrane in response to changes in membrane potential …

The envelope (E) protein of the SARS-CoV-2 virus forms cation-conducting channels in the
endoplasmic reticulum Golgi intermediate compartment (ERGIC) of infected cells. The …

Solid-state nuclear magnetic resonance (ssNMR) methods can probe the motions of
membrane proteins in liposomes at the atomic level and propel the understanding of …

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) are
neurotransmitter-activated cation channels ubiquitously expressed in vertebrate brains. The …

The extremophile bacterium D. radiodurans boasts a distinctive cell envelope characterized
by the regular arrangement of three protein complexes. Among these, the Type II Secretion …

Skeletal muscle contractions are initiated by action potentials, which are sensed by the
voltage-gated calcium channel (CaV1. 1) and are conformationally coupled to calcium …

Channelrhodopsins, light-gated cation channels, enable precise control of neural cell
depolarization or hyperpolarization with light in the field of optogenetics. This study …

Abstract Background and Purpose Pathogenic gain‐of‐function mutations in Cav1. 3 L‐type
voltage‐gated Ca2+‐channels (CACNA1D) cause neurodevelopmental disorders with or …

TRPV6 is a Ca 2+ selective channel that mediates calcium uptake in the gut and contributes
to the development and progression of human cancers. TRPV6 is represented by the …

Some calcium channels selectively permeate Ca2+, despite the high concentration of
monovalent ions in the surrounding environment, which is essential for many physiological …