[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …
impairment and blindness globally. Drug administration through the topical ocular route is …
Functional supramolecular systems: Design and applications
IS Antipin, MV Alfimov, VV Arslanov… - Russian Chemical …, 2021 - iopscience.iop.org
The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …
technologies, able to fundamentally change the world, is growing at a high pace. The huge …
Penetration enhancers in ocular drug delivery
There are more than 100 recognized disorders of the eye. This makes the development of
advanced ocular formulations an important topic in pharmaceutical science. One of the ways …
advanced ocular formulations an important topic in pharmaceutical science. One of the ways …
Supramolecular biopharmaceutical carriers based on host–guest interactions
W Li, W Xu, S Zhang, J Li, J Zhou, D Tian… - Journal of Agricultural …, 2022 - ACS Publications
Traditional drugs have the disadvantages of poor permeability and low solubility, which
makes the utilization of pesticides lower and brings many side effects. With the continuous …
makes the utilization of pesticides lower and brings many side effects. With the continuous …
[HTML][HTML] Integrating stimuli-responsive properties in host-guest supramolecular drug delivery systems
AS Braegelman, MJ Webber - Theranostics, 2019 - ncbi.nlm.nih.gov
Host-guest motifs are likely the most recognizable manifestation of supramolecular
chemistry. These complexes are characterized by the organization of small molecules on the …
chemistry. These complexes are characterized by the organization of small molecules on the …
Review of approaches for increasing ophthalmic bioavailability for eye drop formulations
Ophthalmic diseases represent a significant problem as over 2 billion people worldwide
suffer from vison impairment and blindness. Eye drops account for around 90% of …
suffer from vison impairment and blindness. Eye drops account for around 90% of …
The role of additives on the interaction behavior of levofloxacin hemihydrate with crown ether: UV–visible spectroscopic and DFT techniques
The levofloxacin hemihydrate (LH); a third generation floroquinolone antibiotic drug works
against bacteria by killing bacteria or stopping their growth. But it has some side effects …
against bacteria by killing bacteria or stopping their growth. But it has some side effects …
Recent updates on supramolecular‐based drug delivery–macrocycles and supramolecular gels
VS Saji - The Chemical Record, 2022 - Wiley Online Library
Supramolecules‐based drug delivery has attracted significant recent research attention as it
could enhance drug solubility, retention time, targeting, and stimuli responsiveness. Among …
could enhance drug solubility, retention time, targeting, and stimuli responsiveness. Among …
[HTML][HTML] Chitosan/β-glycerophosphate in situ forming thermo-sensitive hydrogel for improved ocular delivery of moxifloxacin hydrochloride
MH Asfour, SH Abd El-Alim, GEA Awad… - European Journal of …, 2021 - Elsevier
The aim of the current work is to develop a thermo-sensitive hydrogel system of moxifloxacin
hydrochloride (MOX) for improved ocular delivery. Fifteen formulations were prepared at …
hydrochloride (MOX) for improved ocular delivery. Fifteen formulations were prepared at …
Small Molecule Inhibitors Targeting the “Undruggable” Survivin: The Past, Present, and Future from a Medicinal Chemist's Perspective
Survivin, a homodimeric protein and a member of the IAP family, plays a vital function in cell
survival and cycle progression by interacting with various proteins and complexes. Its …
survival and cycle progression by interacting with various proteins and complexes. Its …