Regulation of the cerebral circulation by arterial carbon dioxide

RL Hoiland, JA Fisher, PN Ainslie - Comprehensive Physiology, 2011 - Wiley Online Library
Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …

An intimate crosstalk between iron homeostasis and oxygen metabolism regulated by the hypoxia-inducible factors (HIFs)

K Hirota - Free Radical Biology and Medicine, 2019 - Elsevier
Oxygen and iron are among the most abundant elements and have significant roles in
human biology. Iron is essential for oxygen transport and is a component of molecular O 2 …

Anemia is associated with severe illness in COVID‐19: a retrospective cohort study

Z Tao, J Xu, W Chen, Z Yang, X Xu, L Liu… - Journal of medical …, 2021 - Wiley Online Library
Anemia commonly aggravates the severity of respiratory diseases, whereas thus far, few
studies have elucidated the impact of anemia on coronavirus disease 2019 (COVID‐19) …

[HTML][HTML] Six-month outcomes after restrictive or liberal transfusion for cardiac surgery

CD Mazer, RP Whitlock, DA Fergusson… - … England Journal of …, 2018 - Mass Medical Soc
Background We reported previously that, in patients undergoing cardiac surgery who were
at moderate-to-high risk for death, a restrictive transfusion strategy was noninferior to a …

Perioperative care of patients at high risk for stroke during or after non-cardiac, non-neurological surgery: 2020 guidelines from the Society for Neuroscience in …

PE Vlisides, LE Moore, MK Whalin… - Journal of …, 2020 - journals.lww.com
Perioperative stroke is associated with considerable morbidity and mortality. Stroke
recognition and diagnosis are challenging perioperatively, and surgical patients receive …

Exploring the link between maternal hematological disorders during pregnancy and neurological development in newborns: mixed cohort study

E Bakhsh, M Alkhaldi, M Shaban - Life, 2023 - mdpi.com
Maternal hematological disorders during pregnancy may pose a risk to the neurological
development of newborns. To investigate the association between maternal hematological …

Design strategies for cellular nanosponges as medical countermeasures

S Wang, D Wang, M Kai, WT Shen, L Sun, W Gao… - BME …, 2023 - spj.science.org
The interest in using therapeutic nanoparticles to bind with harmful molecules or pathogens
and subsequently neutralize their bioactivity has grown tremendously. Among various …

Anemia: perioperative risk and treatment opportunity

GMT Hare, CD Mazer - Anesthesiology, 2021 - pubs.asahq.org
Anemia is associated with adverse outcomes in perioperative patients. Understanding the
adaptive cellular and physiologic responses may help define the associated mechanisms …

A mathematical model of cerebral blood flow control in anaemia and hypoxia

J Duffin, GMT Hare, JA Fisher - The Journal of physiology, 2020 - Wiley Online Library
Key points The control of cerebral blood flow in hypoxia, anaemia and hypocapnia is
reviewed with an emphasis on the links between cerebral blood flow and possible stimuli. A …

Potential biomarkers of tissue hypoxia during acute hemodilutional anemia in cardiac surgery: a prospective study to assess tissue hypoxia as a mechanism of organ …

GMT Hare, K Han, Y Leshchyshyn… - Canadian Journal …, 2018 - search.proquest.com
Purpose Hemodilutional anemia is associated with acute kidney injury (AKI) and mortality in
patients undergoing cardiac surgery by mechanisms that may include tissue hypoxia. Our …