Raman imaging of small biomolecules
Imaging techniques greatly facilitate the comprehensive knowledge of biological systems.
Although imaging methodology for biomacromolecules such as protein and nucleic acids …
Although imaging methodology for biomacromolecules such as protein and nucleic acids …
Cholesterol and Lipid Rafts in the Biogenesis of Amyloid-β Protein and Alzheimer's Disease
GA Pantelopulos, CB Abraham… - Annual Review of …, 2024 - annualreviews.org
Cholesterol has been conjectured to be a modulator of the amyloid cascade, the mechanism
that produces the amyloid-β (Aβ) peptides implicated in the onset of Alzheimer's disease …
that produces the amyloid-β (Aβ) peptides implicated in the onset of Alzheimer's disease …
Three-dimensional operando optical imaging of particle and electrolyte heterogeneities inside Li-ion batteries
Understanding (de) lithiation heterogeneities in battery materials is key to ensure optimal
electrochemical performance. However, this remains challenging due to the three …
electrochemical performance. However, this remains challenging due to the three …
Single‐Molecule 3D Orientation Imaging Reveals Nanoscale Compositional Heterogeneity in Lipid Membranes
In soft matter, thermal energy causes molecules to continuously translate and rotate, even in
crowded environments, thereby impacting the spatial organization and function of most …
crowded environments, thereby impacting the spatial organization and function of most …
Fast compressive Raman bio-imaging via matrix completion
Raman microscopy is a powerful method combining non-invasiveness with no special
sample preparation. Because of this remarkable simplicity, it has been widely exploited in …
sample preparation. Because of this remarkable simplicity, it has been widely exploited in …
[HTML][HTML] Dynamic pattern generation in cell membranes: Current insights into membrane organization
K Raghunathan, AK Kenworthy - Biochimica et Biophysica Acta (BBA) …, 2018 - Elsevier
It has been two decades since the lipid raft hypothesis was first presented. Even today,
whether these nanoscale cholesterol-rich domains are present in cell membranes is not …
whether these nanoscale cholesterol-rich domains are present in cell membranes is not …
Quantitative label-free imaging of lipid domains in single bilayers by hyperspectral coherent Raman scattering
A Nahmad-Rohen, D Regan, F Masia… - Analytical …, 2020 - ACS Publications
Lipid phase separation in cellular membranes is thought to play an important role in many
biological functions. This has prompted the development of synthetic membranes to study …
biological functions. This has prompted the development of synthetic membranes to study …
Regimes of complex lipid bilayer phases induced by cholesterol concentration in MD simulation
GA Pantelopulos, JE Straub - Biophysical journal, 2018 - cell.com
Cholesterol is essential to the formation of phase-separated lipid domains in membranes.
Lipid domains can exist in different thermodynamic phases depending on the molecular …
Lipid domains can exist in different thermodynamic phases depending on the molecular …
Raman spectra of deuterated hydrocarbons for labeling applications
KA Okotrub, DV Shamaeva… - Journal of Raman …, 2022 - Wiley Online Library
Raman spectroscopy is used for studying the composition of cell lipidome. However, the
Raman approach suffers from limited distinguish power for different lipids. In recent years …
Raman approach suffers from limited distinguish power for different lipids. In recent years …
Evaluating pathological levels of intracellular cholesterol through Raman and surface-enhanced Raman spectroscopies
Versatile methods for the quantification of intracellular cholesterol are essential for
understanding cellular physiology and for diagnosing disorders linked to cholesterol …
understanding cellular physiology and for diagnosing disorders linked to cholesterol …