Global burden of hepatitis B virus: current status, missed opportunities and a call for action

YC Hsu, DQ Huang, MH Nguyen - Nature Reviews Gastroenterology & …, 2023 - nature.com
Chronic hepatitis B virus (HBV) infection affects about 296 million people worldwide and is
the leading aetiology of cirrhosis and liver cancer globally. Major medical complications also …

Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission

GS Cooke, I Andrieux-Meyer, TL Applegate… - The lancet …, 2019 - thelancet.com
Viral hepatitis is a major public health threat and a leading cause of death worldwide.
Annual mortality from viral hepatitis is similar to that of other major infectious diseases such …

Systematic review and individual-patient-data meta-analysis of non-invasive fibrosis markers for chronic hepatitis B in Africa

A Johannessen, AJ Stockdale, MYR Henrion… - Nature …, 2023 - nature.com
Abstract In sub-Saharan Africa, simple biomarkers of liver fibrosis are needed to scale-up
hepatitis B treatment. We conducted an individual participant data meta-analysis of 3,548 …

A global investment framework for the elimination of hepatitis B

J Howell, A Pedrana, SE Schroeder, N Scott… - Journal of …, 2021 - Elsevier
Background & Aims More than 292 million people are living with hepatitis B worldwide and
are at risk of death from cirrhosis and liver cancer. The World Health Organization (WHO) …

Development and evaluation of a simple treatment eligibility score (HEPSANET) to decentralise hepatitis B care in Africa: a cross-sectional study

N Minier, AN Guingané, E Okeke, E Sinkala… - The Lancet …, 2024 - thelancet.com
Summary Background Hepatitis B virus (HBV) elimination requires expanding and
decentralising HBV care services. However, peripheral health facilities lack access to …

[PDF][PDF] Rapid point-of-care test for hepatitis B core-related antigen to diagnose high viral load in resource-limited settings

Y Shimakawa, G Ndow, A Kaneko, K Aoyagi… - Clinical …, 2023 - Elsevier
Study concept and design, YS, YT; acquisition of data, YS, GN, AC, AK, AH, NY, KA, ML;
analysis and interpretation of data, YS, TC, AK, KA, JPV, ML, YT; drafting of the manuscript …

Hepatitis B virus seroepidemiology data for Africa: Modelling intervention strategies based on a systematic review and meta-analysis

AL McNaughton, J Lourenço, PA Bester… - PLoS …, 2020 - journals.plos.org
Background International Sustainable Development Goals (SDGs) for elimination of
hepatitis B virus (HBV) infection set ambitious targets for 2030. In African populations, infant …

Point-of-care tests for hepatitis B: an overview

Y Xiao, AJ Thompson, J Howell - Cells, 2020 - mdpi.com
Despite the heavy disease burden posed by hepatitis B, around 90% of people living with
hepatitis B are not diagnosed globally. Many of the affected populations still have limited or …

Hepatocellular carcinoma: measures to improve the outlook in sub-Saharan Africa

CW Spearman, G Dusheiko, E Jonas… - The Lancet …, 2022 - thelancet.com
Hepatocellular carcinoma is a leading public health concern in sub-Saharan Africa, and it is
most prevalent in young adults (median 45 years [IQR 35–57]). Overall, outcomes are poor …

WHO guidelines for prevention, care and treatment of individuals infected with HBV: a US perspective

A Vittal, MG Ghany - Clinics in liver disease, 2019 - liver.theclinics.com
More than 2 billion people have been exposed to the hepatitis B virus (HBV) of whom an
estimated 257 million people have chronic infection. 1 Chronic HBV infection occurs globally …