[HTML][HTML] Pathophysiology of atherosclerosis
S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
The changing landscape of atherosclerosis
P Libby - Nature, 2021 - nature.com
Emerging evidence has spurred a considerable evolution of concepts relating to
atherosclerosis, and has called into question many previous notions. Here I review this …
atherosclerosis, and has called into question many previous notions. Here I review this …
Endothelial shear stress signal transduction and atherogenesis: from mechanisms to therapeutics
Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …
[HTML][HTML] More than just a monolayer: the multifaceted role of endothelial cells in the pathophysiology of atherosclerosis
M Mussbacher, K Schossleitner… - Current atherosclerosis …, 2022 - Springer
Abstract Purpose of the Review In this review, we summarize current insights into the
versatile roles of endothelial cells in atherogenesis. Recent Findings The vascular …
versatile roles of endothelial cells in atherogenesis. Recent Findings The vascular …
Transcytosis-enabled active extravasation of tumor nanomedicine
Extravasation is the first step for nanomedicines in circulation to reach targeted solid tumors.
Traditional nanomedicines have been designed to extravasate into tumor interstitium …
Traditional nanomedicines have been designed to extravasate into tumor interstitium …
ROS responsive nanoparticles loaded with lipid-specific AIEgen for atherosclerosis-targeted diagnosis and bifunctional therapy
Atherosclerosis, which is triggered by endothelial damage, progressive local inflammation
and excessive lipid accumulation, is one of the most common cardiovascular diseases in …
and excessive lipid accumulation, is one of the most common cardiovascular diseases in …
[HTML][HTML] Deacetylation of Caveolin-1 by Sirt6 induces autophagy and retards high glucose-stimulated LDL transcytosis and atherosclerosis formation
Y Zhao, X Jia, X Yang, X Bai, Y Lu, L Zhu, W Cheng… - Metabolism, 2022 - Elsevier
Background Atherosclerosis (AS) is the basis of diabetic macrovascular complications. The
plasma low-density lipoprotein (LDL) particles transcytosis across endothelial cells (ECs) …
plasma low-density lipoprotein (LDL) particles transcytosis across endothelial cells (ECs) …
[HTML][HTML] Autophagy, pyroptosis, and ferroptosis: new regulatory mechanisms for atherosclerosis
L Lin, MX Zhang, L Zhang, D Zhang, C Li… - Frontiers in cell and …, 2022 - frontiersin.org
Atherosclerosis is a chronic inflammatory disorder characterized by the gradual buildup of
plaques within the vessel wall of middle-sized and large arteries. The occurrence and …
plaques within the vessel wall of middle-sized and large arteries. The occurrence and …
Cav-1 (Caveolin-1) deficiency increases autophagy in the endothelium and attenuates vascular inflammation and atherosclerosis
Objective: Endothelial Cav-1 (caveolin-1) expression plays a relevant role during
atherogenesis by controlling NO production, vascular inflammation, LDL (low-density …
atherogenesis by controlling NO production, vascular inflammation, LDL (low-density …
Caveolae: Mechanosensing and mechanotransduction devices linking membrane trafficking to mechanoadaptation
MA Del Pozo, FN Lolo, A Echarri - Current opinion in cell biology, 2021 - Elsevier
Mechanical forces (extracellular matrix stiffness, vascular shear stress, and muscle
stretching) reaching the plasma membrane (PM) determine cell behavior. Caveolae are PM …
stretching) reaching the plasma membrane (PM) determine cell behavior. Caveolae are PM …