Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …

GlycoRNA consists of RNAs modified with secretory N-glycans that are presented on the cell
surface. Although previous work supported a covalent linkage between RNA and glycans …

The fucosylation of glycoproteins regulates diverse physiological processes. Inhibitors that
can control cellular levels of protein fucosylation have consequently emerged as being of …

L-Lactylation is a recently discovered post-translational modification occurring on histone
lysine residues to regulate gene expression. However, the substrate scope of lactylation …

Metabolic oligosaccharide engineering (MOE) is a classical chemical approach to perturb,
profile and perceive glycans in physiological systems, but probes upon bioorthogonal …

Mucins represent a largely untapped class of polymeric building block for biomaterials,
therapeutics, and other biotechnology. Because the mucin polymer backbone is genetically …

Microalgae has the capability to replace petroleum-based fuels and is a promising option as
an energy feedstock because of its fast growth, high photosynthetic capacity and remarkable …

Metabolic oligosaccharide engineering (MOE) has fundamentally contributed to our
understanding of protein glycosylation. Efficient MOE reagents are activated into nucleotide …

Azido sugars have found frequent use as probes of biological systems in approaches
ranging from cell surface metabolic labeling to activity-based proteomic profiling of …