A multitude of pharmacological compounds have been shown to lower and control
intraocular pressure (IOP) in numerous species of animals and human subjects after topical …

More than 76 million people worldwide are afflicted with the neurodegenerative eye
diseases described and grouped together as glaucoma. A common feature amongst the …

Although the visual system extends through the brain, most vision loss originates from
defects in the eye. Its central element is the neural retina, which senses light, processes …

Primary open-angle glaucoma (POAG), characterized by retinal ganglion cell death, is a
leading cause of irreversible blindness worldwide. However, its molecular and cellular …

Clinical evidence shows that intraocular hypertension is not the primary pathogenetic event
of glaucoma, whereas early neurodegeneration of retinal ganglion cells (RGCs) represents …

The relationship between gut microbiota and glaucoma has garnered significant interest,
with emerging evidence suggesting that gut dysbiosis, inflammation, and immune …

Primary open-angle glaucoma (POAG) is the most common type of glaucoma leading to
blindness. The search for ways to prevent/treat this entity is one of the main challenges of …

Processes that damage the optic nerve, including elevated intraocular pressure, trauma,
ischemia, and compression, often cause visual loss for which there is no current treatment. It …

Objective: To assess the impact of microgravity exposure on ocular rigidity (OR), intraocular
pressure (IOP), and ocular pulse amplitude (OPA) following long-term space missions. OR …

Pathologic bidirectional interactions between the extracellular matrix (ECM) and cells within
the human trabecular meshwork (hTM) contribute to ocular hypertension. An in vitro model is …