Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment
The pathways of intracellular traffic involved in antigen processing and presentation have
been defined by immunoelectron microscopy. The export pathway for class II …
been defined by immunoelectron microscopy. The export pathway for class II …
Mass spectrometry–based identification of MHC-bound peptides for immunopeptidomics
Peptide antigens bound to molecules encoded by the major histocompatibility complex
(MHC) and presented on the cell surface form the targets of T lymphocytes. This critical arm …
(MHC) and presented on the cell surface form the targets of T lymphocytes. This critical arm …
Human gut-derived commensal bacteria suppress CNS inflammatory and demyelinating disease
The human gut is colonized by a large number of microorganisms (∼ 10 13 bacteria) that
support various physiologic functions. A perturbation in the healthy gut microbiome might …
support various physiologic functions. A perturbation in the healthy gut microbiome might …
Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens
Cancer somatic mutations can generate neoantigens that distinguish malignant from normal
cells,,,,,,. However, the personalized identification and validation of neoantigens remains a …
cells,,,,,,. However, the personalized identification and validation of neoantigens remains a …
Identification of HLA-DR–bound peptides presented by human bronchoalveolar lavage cells in sarcoidosis
Sarcoidosis is an inflammatory disease of unknown etiology, most commonly affecting the
lungs. Activated CD4+ T cells accumulate in the lungs of individuals with sarcoidosis and …
lungs. Activated CD4+ T cells accumulate in the lungs of individuals with sarcoidosis and …
Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.
R de Waal Malefyt, J Abrams, B Bennett… - The Journal of …, 1991 - rupress.org
In the present study we demonstrate that human monocytes activated by
lipopolysaccharides (LPS) were able to produce high levels of interleukin 10 (IL-10) …
lipopolysaccharides (LPS) were able to produce high levels of interleukin 10 (IL-10) …
Identification and characterization of a novel monocyte subpopulation in human peripheral blood
B Passlick, D Flieger, HW Ziegler-Heitbrock - 1989 - ashpublications.org
With the aid of two-color immunofluorescence and flow cytometry, a new subset of cells
coexpressing CD14 and CD16 antigens can be identified in human peripheral blood. Using …
coexpressing CD14 and CD16 antigens can be identified in human peripheral blood. Using …
Unexpected abundance of HLA class II presented peptides in primary renal cell carcinomas
J Dengjel, MD Nastke, C Gouttefangeas… - Clinical cancer …, 2006 - AACR
Purpose: To elicit a long-lasting antitumor immune response, CD8+ and CD4+ T cells
should be activated. We attempted to isolate HLA-DR–presented peptides directly from …
should be activated. We attempted to isolate HLA-DR–presented peptides directly from …
T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein.
S Stemme, B Faber, J Holm… - Proceedings of the …, 1995 - National Acad Sciences
Atherosclerosis, an underlying cause of myocardial infarction, stroke, and other
cardiovascular diseases, consists of focal plaques characterized by cholesterol deposition …
cardiovascular diseases, consists of focal plaques characterized by cholesterol deposition …
Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease
J Rogers, J Luber-Narod, SD Styren, WH Civin - Neurobiology of aging, 1988 - Elsevier
HLA-DR is a class II major histocompatibility complex antigen which in the periphery confers
antigen presenting capability. We have previously shown that this marker is profusely …
antigen presenting capability. We have previously shown that this marker is profusely …