Biological importance of structurally diversified chromenes

M Costa, TA Dias, A Brito, F Proença - European journal of medicinal …, 2016 - Elsevier
Compounds incorporating the chromene scaffold are largely present in natural products and
display a wide variety of biological activities. Their low toxicity combined to the broad …

A decennary update on applications of metal nanoparticles (MNPs) in the synthesis of nitrogen-and oxygen-containing heterocyclic scaffolds

TM Dhameliya, HA Donga, PV Vaghela, BG Panchal… - RSC …, 2020 - pubs.rsc.org
Heterocycles have been found to be of much importance as several nitrogen-and oxygen-
containing heterocycle compounds exist amongst the various USFDA-approved drugs …

Recent Advances in Squaramide‐Catalyzed Asymmetric Mannich Reactions

XQ Hou, DM Du - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
Bifunctional squaramides as a branch of organo‐catalysts showed powerful strategies in the
art of asymmetric synthesis, and they have been proved to be highly efficient and versatile …

Organocatalytic Asymmetric Synthesis of Six‐Membered Carbocycle‐Based Spiro Compounds

X Xie, W Huang, C Peng, B Han - Advanced Synthesis & …, 2018 - Wiley Online Library
Well‐developed asymmetric organocatalysis has been widely incorporated in various
cascade/tandem sequences, providing a simple access to structurally complex target …

Green and mechanochemical one-pot multicomponent synthesis of bioactive 2-amino-4 H-benzo [b] pyrans via highly efficient amine-functionalized SiO2@ Fe3O4 …

P Singh, P Yadav, A Mishra, SK Awasthi - ACS omega, 2020 - ACS Publications
An ecofriendly, magnetically retrievable amine-functionalized SiO2@ Fe3O4 catalyst was
successfully synthesized and affirmed by several physicochemical characterization tools …

Recyclable mesalamine-functionalized magnetic nanoparticles (mesalamine/GPTMS@ SiO 2@ Fe 3 O 4) for tandem Knoevenagel–Michael cyclocondensation …

M Partovi, S Rezayati, A Ramazani, Y Ahmadi… - RSC …, 2023 - pubs.rsc.org
In the present study, mesalamine-functionalized on magnetic nanoparticles
(mesalamine/GPTMS@ SiO2@ Fe3O4) is fabricated as an efficient and magnetically …

[HTML][HTML] Tubulin inhibitors. Selected scaffolds and main trends in the design of novel anticancer and antiparasitic agents

M Podolak, S Holota, Y Deyak, K Dziduch… - Bioorganic …, 2024 - Elsevier
Abstract Design of tubulin inhibitors as anticancer drugs dynamically developed over the
past 20 years. The modern arsenal of potential tubulin-targeting anticancer agents is …

Navigating the synthesis of quinoline hybrid molecules as promising anticancer agents

P Panda, S Chakroborty - ChemistrySelect, 2020 - Wiley Online Library
The emergence of drug resistance and low specificity with side effects are the significant
challenges in pharmaceutical sectors for control of cancer nowadays. Notwithstanding, this …

Tubulin colchicine binding site inhibitors as vascular disrupting agents in clinical developments

YT Ji, YN Liu, ZP Liu - Current medicinal chemistry, 2015 - ingentaconnect.com
Tumor vasculature is an important target in cancer treatment. Two distinct vasculartargeting
therapeutic strategies are applied to attack cancer cells indirectly. The antiangiogenic …

Indolyl-4H-chromenes: Multicomponent one-pot green synthesis, in vitro and in silico, anticancer and antioxidant studies

P Anaikutti, M Selvaraj, J Prabhakaran… - Journal of Molecular …, 2022 - Elsevier
The present work describes the simple, economical and eco-friendly multicomponent one-
pot synthesis of indolyl-4H-chromene derivatives. It is being achieved by reacting …