Vitamin D and multiple sclerosis

A Ascherio, KL Munger, KC Simon - The Lancet Neurology, 2010 - thelancet.com
The hypothesis that adequate vitamin D nutrition can contribute to the prevention of multiple
sclerosis (MS) was originally proposed to explain the geographical distribution of MS, but …

Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity

DL Kamen, V Tangpricha - Journal of molecular medicine, 2010 - Springer
Vitamin D has received increased attention recently for its pleiotropic actions on many
chronic diseases. The importance of vitamin D on the regulation of cells of the immune …

Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis

S Simpson, L Blizzard, P Otahal… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background There is a striking latitudinal gradient in multiple sclerosis (MS) prevalence, but
exceptions in Mediterranean Europe and northern Scandinavia, and some systematic …

Vitamin D in neurological diseases: a rationale for a pathogenic impact

R Moretti, ME Morelli, P Caruso - International journal of molecular …, 2018 - mdpi.com
It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Respiratory viral infections and the risk of rheumatoid arthritis

YB Joo, YH Lim, KJ Kim, KS Park, YJ Park - Arthritis research & therapy, 2019 - Springer
Background We aimed to investigate the effects of ambient respiratory viral infections in the
general population on rheumatoid arthritis (RA) development. Methods Data of weekly …

Higher 25‐hydroxyvitamin D is associated with lower relapse risk in multiple sclerosis

S Simpson Jr, B Taylor, L Blizzard… - Annals of …, 2010 - Wiley Online Library
Objective A protective association between higher vitamin D levels and the onset of multiple
sclerosis (MS) has been demonstrated; however, its role in modulating MS clinical course …

Asymptomatic embolisation for prediction of stroke in the Asymptomatic Carotid Emboli Study (ACES): a prospective observational study

HS Markus, A King, M Shipley, R Topakian… - The Lancet …, 2010 - thelancet.com
Background Whether surgery is beneficial for patients with asymptomatic carotid stenosis is
controversial. Better methods of identifying patients who are likely to develop stroke would …

Smoking and multiple sclerosis: an updated meta-analysis

AE Handel, AJ Williamson, G Disanto, R Dobson… - PloS one, 2011 - journals.plos.org
Background Multiple sclerosis (MS) is a leading cause of disability in young adults.
Susceptibility to MS is determined by environmental exposure on the background of genetic …

The role of infections in multiple sclerosis

M Marrodan, L Alessandro, MF Farez… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Several lines of evidence suggest that multiple sclerosis (MS), like other autoimmune
diseases, may be triggered by microbial infections. Pathogens associated with development …

Seasonality and autoimmune diseases: the contribution of the four seasons to the mosaic of autoimmunity

A Watad, S Azrielant, NL Bragazzi, K Sharif… - Journal of …, 2017 - Elsevier
Autoimmune diseases (ADs) are a heterogeneous groups of diseases that occur as a results
of loss of tolerance to self antigens. While the etiopathogeneis remain obscure, different …