[HTML][HTML] Molecular mechanisms and emerging therapeutics for osteoporosis

JY Noh, Y Yang, H Jung - International journal of molecular sciences, 2020 - mdpi.com
Osteoporosis is the most common chronic metabolic bone disease. It has been estimated
that more than 10 million people in the United States and 200 million men and women …

[HTML][HTML] Association between obesity and risk of fracture, bone mineral density and bone quality in adults: a systematic review and meta-analysis

AF Turcotte, S O'Connor, SN Morin, JC Gibbs… - PloS one, 2021 - journals.plos.org
Background The association between obesity and fracture risk may be skeletal site-and sex-
specific but results among studies are inconsistent. Whilst several studies reported higher …

Epidemiology of vertebral fractures

JT Schousboe - Journal of Clinical Densitometry, 2016 - Elsevier
Vertebral fractures are one of the most common fractures associated with skeletal fragility
and can cause as much morbidity as hip fractures. However, the epidemiology of vertebral …

Strength training stops bone loss and builds muscle in postmenopausal breast cancer survivors: a randomized, controlled trial

KM Winters-Stone, J Dobek, L Nail, JA Bennett… - Breast cancer research …, 2011 - Springer
Targeted exercise training could reduce risk factors for fracture and obesity-related diseases
that increase from breast cancer treatment, but has not been sufficiently tested. We …

Fracture mortality: associations with epidemiology and osteoporosis treatment

SE Sattui, KG Saag - Nature Reviews Endocrinology, 2014 - nature.com
The rates of incident osteoporotic fractures seem to be stabilizing; however, fragility fractures
are still associated with considerable disability, costs and an increased risk of mortality …

Quality of life assessment in musculo-skeletal health

C Beaudart, E Biver, O Bruyère, C Cooper… - Aging clinical and …, 2018 - Springer
Musculoskeletal disorders affect morbidity, quality of life and mortality, and represent an
increasing economic and societal burden in the context of population aging and increased …

The global burden attributable to low bone mineral density

L Sànchez-Riera, E Carnahan, T Vos… - Annals of the …, 2014 - ard.bmj.com
Introduction The Global Burden of Disease Study 2010 estimated the worldwide health
burden of 291 diseases and injuries and 67 risk factors by calculating disability-adjusted life …

Association between drug treatments for patients with osteoporosis and overall mortality rates: a meta-analysis

SR Cummings, LY Lui, R Eastell… - JAMA internal medicine, 2019 - jamanetwork.com
Importance Previous studies have reported that drug treatments, particularly treatment with
bisphosphonates, is associated with reduced overall mortality rates in addition to decreased …

[HTML][HTML] Mortality in older adults following a fragility fracture: real-world retrospective matched-cohort study in Ontario

JP Brown, JD Adachi, E Schemitsch, JE Tarride… - BMC musculoskeletal …, 2021 - Springer
Background Recent studies are lacking reports on mortality after non-hip fractures in adults
aged> 65. Methods This retrospective, matched-cohort study used de-identified health …

[HTML][HTML] Direct health-care costs attributed to hip fractures among seniors: a matched cohort study

M Nikitovic, WP Wodchis, MD Krahn… - Osteoporosis …, 2013 - Springer
Using a matched cohort design, we estimated the mean direct attributable cost in the first
year after hip fracture in Ontario to be 36,929amongwomenand 39,479 among men. These …