Blood-brain barrier disruption: a culprit of cognitive decline?
J Che, Y Sun, Y Deng, J Zhang - Fluids and Barriers of the CNS, 2024 - Springer
Cognitive decline covers a broad spectrum of disorders, not only resulting from brain
diseases but also from systemic diseases, which seriously influence the quality of life and …
diseases but also from systemic diseases, which seriously influence the quality of life and …
Risk factors in developing amyloid related imaging abnormalities (ARIA) and clinical implications
SJ Doran, RP Sawyer - Frontiers in Neuroscience, 2024 - frontiersin.org
Alzheimer's disease (AD) affects over 6 million people over the age of 65. The advent of new
anti-amyloid monoclonal antibodies as treatment for early Alzheimer's disease these …
anti-amyloid monoclonal antibodies as treatment for early Alzheimer's disease these …
Immune system activation and cognitive impairment in arterial hypertension
Chronic arterial hypertension disrupts the integrity of the cerebral microvasculature,
doubling the risk of age-related dementia. Despite sufficient antihypertensive therapy in still …
doubling the risk of age-related dementia. Despite sufficient antihypertensive therapy in still …
Pathophysiology of cerebral small vessel disease: a journey through recent discoveries
Cerebral small vessel disease (cSVD) encompasses a heterogeneous group of age-related
small vessel pathologies that affect multiple regions. Disease manifestations range from …
small vessel pathologies that affect multiple regions. Disease manifestations range from …
Perivascular space dysfunction in cerebral small vessel disease is related to neuroinflammation
Enlarged perivascular spaces are a feature of cerebral small vessel disease, and it has
been hypothesized that they may reflect impaired glymphatic drainage. The mechanisms …
been hypothesized that they may reflect impaired glymphatic drainage. The mechanisms …
[HTML][HTML] Assessing Mild Traumatic Brain Injury-Associated Blood–Brain Barrier (BBB) Damage and Restoration Using Late-Phase Perfusion Analysis by 3D ASL MRI …
CR Joseph - International Journal of Molecular Sciences, 2024 - mdpi.com
Mild traumatic brain injury (mTBI) is a common occurrence around the world, associated with
a variety of blunt force and torsion injuries affecting all age groups. Most never reach …
a variety of blunt force and torsion injuries affecting all age groups. Most never reach …
The neurovascular unit and its correlation with cognitive performance in patients with cerebral small vessel disease: a canonical correlation analysis approach
M van Dinther, PHM Voorter, E Zhang, SMJ van Kuijk… - GeroScience, 2024 - Springer
Growing evidence indicates an important role of neurovascular unit (NVU) dysfunction in the
pathophysiology of cerebral small vessel disease (cSVD). Individually measurable functions …
pathophysiology of cerebral small vessel disease (cSVD). Individually measurable functions …
Exploring the Neural Mechanisms of Mirrored‐Self Misidentification in Alzheimer's Disease
Z Sun, G Chen, J Gan, Y Tang, H Wu… - … Journal of Geriatric …, 2024 - Wiley Online Library
Objective Alzheimer's disease (AD) is a complex neurodegenerative condition that causes a
range of cognitive disturbances, including mirror‐self misidentification syndrome (MSM), in …
range of cognitive disturbances, including mirror‐self misidentification syndrome (MSM), in …
Linking peripheral atherosclerosis to blood–brain barrier disruption: elucidating its role as a manifestation of cerebral small vessel disease in vascular cognitive …
Aging plays a pivotal role in the pathogenesis of cerebral small vessel disease (CSVD),
contributing to the onset and progression of vascular cognitive impairment and dementia …
contributing to the onset and progression of vascular cognitive impairment and dementia …
Parenchymal CSF fraction is a measure of brain glymphatic clearance and positively associated with amyloid beta deposition on PET
INTRODUCTION Mapping of microscopic changes in the perivascular space (PVS) of the
cerebral cortex, beyond magnetic resonance‐visible PVS in white matter, may enhance our …
cerebral cortex, beyond magnetic resonance‐visible PVS in white matter, may enhance our …