Barbiturates: A review of synthesis and antimicrobial research progress
Background: Barbituric acid and its derivatives have gained significant attention for several
years as an indispensable class of compounds in the pharmaceutical industry due to their …
years as an indispensable class of compounds in the pharmaceutical industry due to their …
Synthesis and antimicrobial activities of indole-based Schiff bases and their metal complexes: a review
Heterocyclic compounds containing nitrogen have emerged as crucial entities in the realm
of medicinal chemistry. Among these, Schiff bases derived from indole or compounds …
of medicinal chemistry. Among these, Schiff bases derived from indole or compounds …
Structure-based drug designing
The number of three-dimensional (3D) structures of macromolecule/drug targets determined
by experimental techniques has risen over the past years. Besides, the development and …
by experimental techniques has risen over the past years. Besides, the development and …
Survey of New, Small-Molecule Isatin-Based Oxindole Hybrids as Multi-Targeted Drugs for the Treatment of Alzheimer's Disease
CS Marques, Ó López, L Leitzbach… - …, 2022 - thieme-connect.com
In the last decade, our group has been very active at developing and assaying complex
libraries of scaffolds with a focus on their potential to identify bioactive drug candidates for …
libraries of scaffolds with a focus on their potential to identify bioactive drug candidates for …
Synthesis, reaction and biological importance of isatin derivatives
MGA Al-Khuzaie, MM Fahad… - … and Chemical Sciences, 2022 - journals.irapa.org
1Heterocyclic compounds are a type of organic compounds that exhibit a wide range of
biological and pharmacological activities. One such biologically active heterocyclic …
biological and pharmacological activities. One such biologically active heterocyclic …
Heterocyclic Moieties as Prospective Nematicides: An Overview
Plant parasitic nematodes are destructive endoparasites having deleterious effect on about
5000 agricultural crops notably vegetables, fruits, field crops, ornamental plants, and even …
5000 agricultural crops notably vegetables, fruits, field crops, ornamental plants, and even …
Harnessing the potential of omics for prevention and management of the complex crop plant's diseases
Crop plants are hosting a variety of microorganisms in their surroundings, some are
beneficial, but others are causing diseases that account for huge financial losses to the …
beneficial, but others are causing diseases that account for huge financial losses to the …
Schiff Bases of Indole-3-Carbaldehyde: Synthesis and Evaluation as Antimicrobial Agents
A series of Schiff bases of indole-3-carbaldehyde were synthesized by the condensation
reaction of indole-3-carbaldehyde with different aryl amines. The reaction of indole-3 …
reaction of indole-3-carbaldehyde with different aryl amines. The reaction of indole-3 …
A Convenient One-Pot Synthesis of Bis (indolyl) methane Derivatives and Evaluation of Their Nematicidal Activity against the Root Knot Nematode Meloidogyne …
M Rani, D Utreja, NK Dhillon, K Kaur - Russian Journal of Organic …, 2022 - Springer
Seven arylbis (indolyl) methanes were synthesized by electrophilic substitution reaction of
aromatic aldehydes on indole using glacial acetic acid as catalyst in aqueous media under …
aromatic aldehydes on indole using glacial acetic acid as catalyst in aqueous media under …
Efficient p-Toluenesulfonic Acid-Catalyzed Synthesis of 5-Aryl-5,10-dihydropyrimido[4,5-b]quinoline-2,4(1H,3H)-diones and Their Antimicrobial Activity
A simple, practical, and efficient one-pot three-component protocol was employed for the
synthesis of functionalized 5-aryl-5, 10-dihydropyrimido [4, 5-b] quinoline-2, 4 (1 H, 3 H) …
synthesis of functionalized 5-aryl-5, 10-dihydropyrimido [4, 5-b] quinoline-2, 4 (1 H, 3 H) …