Genome control by SMC complexes

C Hoencamp, BD Rowland - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Many cellular processes require large-scale rearrangements of chromatin structure.
Structural maintenance of chromosomes (SMC) protein complexes are molecular machines …

3D genomics across the tree of life reveals condensin II as a determinant of architecture type

C Hoencamp, O Dudchenko, AMO Elbatsh… - Science, 2021 - science.org
We investigated genome folding across the eukaryotic tree of life. We find two types of three-
dimensional (3D) genome architectures at the chromosome scale. Each type appears and …

Chromatin dynamics and subnuclear gene positioning for transcriptional regulation

T Sakamoto, S Matsunaga - Current Opinion in Plant Biology, 2023 - Elsevier
Plants have been found to exhibit diverse characteristics and functions of chromatin
organization, showing both similarities and differences to animals. It is becoming clear how …

Kinetochore and ionomic adaptation to whole-genome duplication in Cochlearia shows evolutionary convergence in three autopolyploids

SM Bray, T Hämälä, M Zhou, S Busoms, S Fischer… - Cell Reports, 2024 - cell.com
Whole-genome duplication (WGD) occurs in all kingdoms and impacts speciation,
domestication, and cancer outcome. However, doubled DNA management can be …

Two-step regulation of centromere distribution by condensin II and the nuclear envelope proteins

T Sakamoto, Y Sakamoto, S Grob, D Slane… - Nature plants, 2022 - nature.com
The arrangement of centromeres within the nucleus differs among species and cell types.
However, neither the mechanisms determining centromere distribution nor its biological …

[HTML][HTML] Mitotic chromosome organization: General rules meet species-specific variability

T Beseda, P Cápal, I Kubalová, V Schubert… - Computational and …, 2020 - Elsevier
Research on the formation of mitotic chromosomes from interphase chromatin domains,
ongoing for several decades, made significant progress in recent years. It was stimulated by …

The mechanisms and significance of the positional control of centromeres and telomeres in plants

Y Oko, N Ito, T Sakamoto - Journal of plant research, 2020 - Springer
The centromere and telomere are universal heterochromatic domains; however, the proper
positioning of those domains in nuclear space during the mitotic interphase differs among …

Linking transcriptional silencing with chromatin remodeling, folding, and positioning in the nucleus

ZW Liu, CH Simmons, X Zhong - Current opinion in plant biology, 2022 - Elsevier
Chromatin organization is important for many DNA-templated processes in eukaryotic cells
such as replication and transcription. Recent studies have uncovered the capacity of …

Kinetochore and ionomic adaptation to whole genome duplication

SM Bray, T Hämälä, M Zhou, S Busoms, S Fischer… - BioRxiv, 2023 - biorxiv.org
Transforming genomic and cellular landscapes in a single generation, whole genome
duplication (WGD) brings fundamental challenges, but is also associated with diversification …

Spatial modeling of biological patterns shows multiscale organization of Arabidopsis thaliana heterochromatin

J Arpòn, K Sakai, V Gaudin, P Andrey - Scientific reports, 2021 - nature.com
The spatial organization in the cell nucleus is tightly linked to genome functions such as
gene regulation. Similarly, specific spatial arrangements of biological components such as …