Reproductive cycles of the domestic bitch

PW Concannon - Animal reproduction science, 2011 - Elsevier
Domestic dogs are monoestrous, typically non-seasonal, polytocous, spontaneous ovulators
and have a spontaneous luteal phase slightly longer (by approx 5 day) than the 64±1day …

Luteal regression vs. prepartum luteolysis: regulatory mechanisms governing canine corpus luteum function

MP Kowalewski - Reproductive Biology, 2014 - Elsevier
Canine reproductive physiology exhibits several unusual features. Among the most
interesting of these are the lack of an acute luteolytic mechanism, coinciding with the …

Troxerutin protects the mouse kidney from d-galactose-caused injury through anti-inflammation and anti-oxidation

S Fan, Z Zhang, Y Zheng, J Lu, D Wu, Q Shan… - International …, 2009 - Elsevier
This study was carried out to investigate the protective effect of troxerutin against d-
galactose (d-gal)-induced renal injury in mice. Hematoxylin and eosin (H&E) stained …

Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition

MP Kowalewski, HB Beceriklisoy, C Pfarrer… - …, 2010 - rep.bioscientifica.com
Expression of cyclooxygenase 2 (COX2, now known as PTGS2), prostaglandin E2 synthase
(PTGES, PGES), and prostaglandin F2α synthase (PGFS), of the respective receptors …

Time related changes in luteal prostaglandin synthesis and steroidogenic capacity during pregnancy, normal and antiprogestin induced luteolysis in the bitch

MP Kowalewski, HB Beceriklisoy, S Aslan… - Animal Reproduction …, 2009 - Elsevier
In nonpregnant and pregnant dogs the corpora lutea (CL) are the only source of
progesterone (P4) which shows an almost identical secretion pattern until the rapid …

[HTML][HTML] Canine conceptus-maternal communication during maintenance and termination of pregnancy, including the role of species-specific decidualization

MP Kowalewski, MT Pereira, A Kazemian - Theriogenology, 2020 - Elsevier
Among domestic animal species, the reproductive biology of the dog belongs to the most
peculiar. This includes the conceptus-maternal communication and endocrine mechanisms …

EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures

T Minamizaki, Y Yoshiko, K Kozai, JE Aubin, N Maeda - Bone, 2009 - Elsevier
Of the four prostaglandin (PG) E receptor subtypes (EP1–EP4), EP2 and EP4 have been
proposed to mediate the anabolic action of PGE2 on bone formation but comparative …

Expression of genes involved in the embryo–maternal interaction in the early-pregnant canine uterus

E Kautz, A Gram, S Aslan, SS Ay, M Selcuk… - …, 2014 - rep.bioscientifica.com
The cellular mechanisms underlying normal and pathological endometrial bleeding are not
well understood, although abnormalities in the structure of endometrial blood vessels may …

Expression and functional implications of Peroxisome Proliferator—Activated Receptor Gamma (PPARγ) in canine reproductive tissues during normal pregnancy and …

MP Kowalewski, A Meyer, B Hoffmann, S Aslan, A Boos - Theriogenology, 2011 - Elsevier
PPARγ is a nuclear hormone receptor of the PPAR family of transcription factors closely
related to the steroid hormone receptors serving multiple roles in regulating reproductive …

The dog: nonconformist, not only in maternal recognition signaling

MP Kowalewski, A Gram, E Kautz… - Regulation of Implantation …, 2015 - Springer
Although similar at the molecular and cellular levels, endocrine mechanisms governing
reproductive function in the domestic dog (Canis familiaris) differ markedly at the regulatory …