Molecular biologist's guide to proteomics
PR Graves, TAJ Haystead - Microbiology and molecular biology …, 2002 - Am Soc Microbiol
The emergence of proteomics, the large-scale analysis of proteins, has been inspired by the
realization that the final product of a gene is inherently more complex and closer to function …
realization that the final product of a gene is inherently more complex and closer to function …
Metabolomics in systems biology
W Weckwerth - Annual review of plant biology, 2003 - annualreviews.org
The primary aim of “omic” technologies is the nontargeted identification of all gene products
(transcripts, proteins, and metabolites) present in a specific biological sample. By their …
(transcripts, proteins, and metabolites) present in a specific biological sample. By their …
Protein labeling by iTRAQ: a new tool for quantitative mass spectrometry in proteome research
S Wiese, KA Reidegeld, HE Meyer, B Warscheid - Proteomics, 2007 - Wiley Online Library
A novel, MS‐based approach for the relative quantification of proteins, relying on the
derivatization of primary amino groups in intact proteins using isobaric tag for relative and …
derivatization of primary amino groups in intact proteins using isobaric tag for relative and …
[HTML][HTML] Proteomics: the first decade and beyond
SD Patterson, RH Aebersold - Nature genetics, 2003 - nature.com
Proteomics is the systematic study of the many and diverse properties of proteins in a
parallel manner with the aim of providing detailed descriptions of the structure, function and …
parallel manner with the aim of providing detailed descriptions of the structure, function and …
AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins
M Ferro, S Brugière, D Salvi… - Molecular & Cellular …, 2010 - ASBMB
Recent advances in the proteomics field have allowed a series of high throughput
experiments to be conducted on chloroplast samples, and the data are available in several …
experiments to be conducted on chloroplast samples, and the data are available in several …
Multiplexed and data‐independent tandem mass spectrometry for global proteome profiling
JD Chapman, DR Goodlett… - Mass spectrometry …, 2014 - Wiley Online Library
One of the most important early developments in the field of proteomics was the advent of
automated data acquisition routines that allowed high‐throughput unattended data …
automated data acquisition routines that allowed high‐throughput unattended data …
Systems toxicology approaches for understanding the joint effects of environmental chemical mixtures
Environmental mixtures of chemicals constitute a prevalent issue in ecotoxicology and the
development of new methods to reduce the uncertainties associated with their ecological …
development of new methods to reduce the uncertainties associated with their ecological …
18O Labeling: a tool for proteomics
II Stewart, T Thomson, D Figeys - Rapid Communications in …, 2001 - Wiley Online Library
An evaluation of the proteolytic labeling and quantification of proteins for diagnostic
purposes using trypsin and 18O‐enriched H2O is presented. We demonstrate that …
purposes using trypsin and 18O‐enriched H2O is presented. We demonstrate that …
Capillary electrophoresis–mass spectrometry: 15 years of developments and applications
P Schmitt‐Kopplin, M Frommberger - Electrophoresis, 2003 - Wiley Online Library
Since its introduction in 1987, capillary electrophoresis‐mass spectrometry (CE‐MS) has
developed to a well accepted multidimensional analytical approach complementary and/or …
developed to a well accepted multidimensional analytical approach complementary and/or …
Proteome analysis by two-dimensional gel electrophoresis and mass spectrometry: strengths and limitations
S Beranova-Giorgianni - TrAC Trends in Analytical Chemistry, 2003 - Elsevier
Two-dimensional gel electrophoresis, mass spectrometry and bioinformatics are the key
components of current proteomics technology. The purpose of this review is to give an …
components of current proteomics technology. The purpose of this review is to give an …