Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

BACKGROUND After recognition of its pivotal contribution to fetomaternal tolerance, the
study of galectin-1 (gal-1) functions in the context of pregnancy became an attractive topic in …

Abstract Galectin-1 (gal-1) is expressed at the feto-maternal interface and plays a role in
regulating the maternal immune response against placental alloantigens, contributing to …

Galectins (Gal) are characterized by their affinity for galactoside structures on
glycoconjugates. This relationship is mediated by carbohydrate recognition domains, which …

Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune
cells remain incompletely understood. In previous studies, we showed that galectin-1 (Gal1) …

Background The decidua has been implicated in the “terminal pathway” of human term
parturition, which is characterized by the activation of pro-inflammatory pathways in …

Successful mammalian pregnancy relies upon acceptance of a semi‐allogeneic fetus by the
maternal immune system. Lessons learned from studies on protective immunity to microbial …

OBJECTIVE: To evaluate the effects of the immunosuppressant tacrolimus on rejection of a
transplanted uterus and on uterine expression of markers of inflammation and implantation …

Growing evidence suggests that galectins, an evolutionarily conserved family of glycan-
binding proteins, fulfill key roles in pregnancy including blastocyst implantation, maternal …

Members of the galectin family are expressed within the female reproductive tract and have
been shown to be involved in multiple biological functions that support the progression of …