At the heart of the interoception network: Influence of the parasubthalamic nucleus on autonomic functions and motivated behaviors

T Shah, JL Dunning, C Contet - Neuropharmacology, 2022 - Elsevier
The parasubthalamic nucleus (PSTN), a small nucleus located on the lateral edge of the
posterior hypothalamus, has emerged in recent years as a highly interconnected node …

Parallels and overlap: the integration of homeostatic signals by mesolimbic dopamine neurons

TM Hsu, JE McCutcheon, MF Roitman - Frontiers in psychiatry, 2018 - frontiersin.org
Motivated behaviors are often initiated in response to perturbations of homeostasis. Indeed,
animals and humans have fundamental drives to procure (appetitive behaviors) and …

A mu–delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks

E Erbs, L Faget, G Scherrer, A Matifas, D Filliol… - Brain Structure and …, 2015 - Springer
Opioid receptors are G protein-coupled receptors (GPCRs) that modulate brain function at
all levels of neural integration, including autonomic, sensory, emotional and cognitive …

The paraventricular hypothalamus regulates satiety and prevents obesity via two genetically distinct circuits

MM Li, JC Madara, JS Steger, MJ Krashes, N Balthasar… - Neuron, 2019 - cell.com
SIM1-expressing paraventricular hypothalamus (PVH) neurons are key regulators of energy
balance. Within the PVH SIM1 population, melanocortin-4 receptor-expressing (PVH MC4R) …

[HTML][HTML] Hindbrain double-negative feedback mediates palatability-guided food and water consumption

R Gong, S Xu, A Hermundstad, Y Yu, SM Sternson - Cell, 2020 - cell.com
Hunger and thirst have distinct goals but control similar ingestive behaviors, and little is
known about neural processes that are shared between these behavioral states. We identify …

The lateral parabrachial nucleus, but not the thalamus, mediates thermosensory pathways for behavioural thermoregulation

T Yahiro, N Kataoka, Y Nakamura, K Nakamura - Scientific reports, 2017 - nature.com
Thermoregulatory behaviour, such as migration to a comfortable thermal environment, is a
representative innate animal behaviour and facilitates effective autonomic regulation of body …

Molecular ontology of the parabrachial nucleus

S Karthik, D Huang, Y Delgado, JJ Laing… - Journal of …, 2022 - Wiley Online Library
Diverse neurons in the parabrachial nucleus (PB) communicate with widespread brain
regions. Despite evidence linking them to a variety of homeostatic functions, it remains …

Efferent projections of CGRP/Calca‐expressing parabrachial neurons in mice

D Huang, FS Grady, L Peltekian… - Journal of …, 2021 - Wiley Online Library
The parabrachial nucleus (PB) is composed of glutamatergic neurons at the midbrain–
hindbrain junction. These neurons form many subpopulations, one of which expresses …

Genetic identity of thermosensory relay neurons in the lateral parabrachial nucleus

JC Geerling, M Kim, CE Mahoney… - American Journal …, 2016 - journals.physiology.org
The parabrachial nucleus is important for thermoregulation because it relays skin
temperature information from the spinal cord to the hypothalamus. Prior work in rats …

Efferent projections of Vglut2, Foxp2, and Pdyn parabrachial neurons in mice

D Huang, FS Grady, L Peltekian… - Journal of Comparative …, 2021 - Wiley Online Library
The parabrachial nucleus (PB) is a complex structure located at the junction of the midbrain
and hindbrain. Its neurons have diverse genetic profiles and influence a variety of …