Cholecystokinin antagonists: pharmacological and therapeutic potential
R Herranz - Medicinal research reviews, 2003 - Wiley Online Library
Cholecystokinin (CCK) is a regulatory peptide hormone, predominantly found in the
gastrointestinal tract, and a neurotransmitter present throughout the nervous system. In the …
gastrointestinal tract, and a neurotransmitter present throughout the nervous system. In the …
Is there a future for neuropeptide receptor ligands in the treatment of anxiety disorders?
G Griebel - Pharmacology & therapeutics, 1999 - Elsevier
This review provides an overview of preclinical and clinical evidence of a role for the
neuroactive peptides cholecystokinin (CCK), corticotropin-releasing factor (CRF) …
neuroactive peptides cholecystokinin (CCK), corticotropin-releasing factor (CRF) …
Перспективы поиска новых анксиолитиков
ТА Воронина, СБ Середенин - Экспериментальная и клиническая …, 2002 - ekf.folium.ru
Аннотация На основании современных знаний о патогенезе стресса, неврозов,
неврозоподобных состояний дано представление о спектре фармакологической …
неврозоподобных состояний дано представление о спектре фармакологической …
Neuronal network of panic disorder: the role of the neuropeptide cholecystokinin
P Zwanzger, K Domschke… - Depression and anxiety, 2012 - Wiley Online Library
Panic disorder (PD) is characterized by panic attacks, anticipatory anxiety and avoidance
behavior. Its pathogenesis is complex and includes both neurobiological and psychological …
behavior. Its pathogenesis is complex and includes both neurobiological and psychological …
The unappreciated roles of the cholecystokinin receptor CCK (1) in brain functioning
S Ballaz - Reviews in the Neurosciences, 2017 - degruyter.com
The CCK (1) receptor is a G-protein-coupled receptor activated by the sulfated forms of
cholecystokinin (CCK), a gastrin-like peptide released in the gastrointestinal tract and …
cholecystokinin (CCK), a gastrin-like peptide released in the gastrointestinal tract and …
Cholecystokinin-mediated neuromodulation of anxiety and schizophrenia: a “dimmer-switch” hypothesis
Cholecystokinin (CCK), the most abundant brain neuropeptide, is involved in relevant
behavioral functions like memory, cognition, and reward through its interactions with the …
behavioral functions like memory, cognition, and reward through its interactions with the …
Spatial memory deficit and emotional abnormality in OLETF rats
XL Li, S Aou, T Hori, Y Oomura - Physiology & behavior, 2002 - Elsevier
Cholecystokinin (CCK) is deeply involved in the control of learning and emotional behaviors.
The authors characterize the behavioral properties of Otsuka Long Evans Tokushima Fatty …
The authors characterize the behavioral properties of Otsuka Long Evans Tokushima Fatty …
β-Turned Dipeptoids as Potent and Selective CCK1 Receptor Antagonists
M Martín-Martínez, N De la Figuera… - Journal of medicinal …, 2000 - ACS Publications
To improve our knowledge of the bioactive conformation of CCK1 antagonists, we previously
described that replacement of the α-MeTrp residue of dipeptoids with the (2 S, 5 S, 11b R)-2 …
described that replacement of the α-MeTrp residue of dipeptoids with the (2 S, 5 S, 11b R)-2 …
Anxiety-related behaviors in cholecystokinin-A, B, and AB receptor gene knockout mice in the plus-maze
K Miyasaka, S Kobayashi, M Ohta, S Kanai… - Neuroscience …, 2002 - Elsevier
Cholecystokinin (CCK)-A receptor (AR) and B receptor (BR) share highly amino acid
sequence homology and overlap in their tissue distribution. We examined the anxiety …
sequence homology and overlap in their tissue distribution. We examined the anxiety …
CCK receptor antagonists
J Dunlop - General Pharmacology: The Vascular System, 1998 - Elsevier
The peptide hormone and neurotransmitter, cholecystokinin, is widely distributed throughout
the gastrointestinal tract and central nervous system and mediates a diverse number of …
the gastrointestinal tract and central nervous system and mediates a diverse number of …