Chiral analysis is of great importance to fundamental and applied research in chemical,
biological and pharmaceutical sciences. Due to the superiority of mass spectrometry (MS) …

As the understanding of the various biological actions of compounds with different
stereochemistry has grown, the necessity to develop methods for the analytical qualification …

In drug development, the combinatorial synthesis of drug libraries is common use, therefore
efficient tools for the characterization of drug candidates and the extent of interaction …

Solution phase and gas phase chiral molecular recognition properties of tartrates (salts or
esters of tartaric acid) and metal tartrates (binuclear tartrato (4‐)‐metal‐bridged complexes) …

Steroid hormones and their metabolites are currently undergoing clinical trials as potential
therapeutics for traumatic brain injury (TBI). To support this work, it is necessary to develop …

The negative ion mode ESI mass spectral analysis of antimony (III)-D-and-L-tartrate (“tartar
emetic”), in association with leucine enantiomeric isotopomers, revealed remarkable proton …

Electrospray ionization-mass spectrometry (ESI-MS) was used to investigate stereoselective
interactions between seven zwitterionic alkylsulfonate-modified cinchona alkaloid chiral …

The most common protocols for the quantitative determination of the enantiomeric excess
(ee) of raw mixtures by ESI-MS reveal inadequate in cases where the distribution of …

Firstly, I would like to thank my supervisor, Professor René Roy, for all his support, patience,
and guidance throughout my entire Ph. D studies and for giving me an opportunity to join his …

Enantioselective discrimination refers to the selective recognition and separation of
enantiomers. Physical and analytical methods that can provide enantioselective …