Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

[HTML][HTML] Abdominal aortic aneurysm: roles of inflammatory cells

Z Yuan, Y Lu, J Wei, J Wu, J Yang, Z Cai - Frontiers in immunology, 2021 - frontiersin.org
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …

[HTML][HTML] The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm

EL Chaikof, RL Dalman, MK Eskandari… - Journal of vascular …, 2018 - Elsevier
Background Decision-making related to the care of patients with an abdominal aortic
aneurysm (AAA) is complex. Aneurysms present with varying risks of rupture, and patient …

Bicuspid aortic valve disease

SC Siu, CK Silversides - Journal of the American College of Cardiology, 2010 - jacc.org
Bicuspid aortic valve (BAV) disease is the most common congenital cardiac defect. While the
BAV can be found in isolation, it is often associated with other congenital cardiac lesions …

[HTML][HTML] The care of patients with an abdominal aortic aneurysm: the Society for Vascular Surgery practice guidelines

EL Chaikof, DC Brewster, RL Dalman… - Journal of vascular …, 2009 - jvascsurg.org
The Clinical Practice Council of the Society for Vascular Surgery charged a writing
committee with the task of updating practice guidelines, initally published in 2003, for …

Atherosclerosis and abdominal aortic aneurysm: cause, response, or common risk factors?

J Golledge, PE Norman - Arteriosclerosis, thrombosis, and …, 2010 - Am Heart Assoc
Abdominal aortic aneurysm (AAA) rupture has been recognized as a significant cause of
mortality for adults aged 60 years in the developed world for some time. 1 AAAs are usually …

Blood flow and coherent vortices in the normal and aneurysmatic aortas: a fluid dynamical approach to intra-luminal thrombus formation

J Biasetti, F Hussain, TC Gasser - Journal of The Royal …, 2011 - royalsocietypublishing.org
Abdominal aortic aneurysms (AAAs) are frequently characterized by the development of an
intra-luminal thrombus (ILT), which is known to have multiple biochemical and …

[HTML][HTML] Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach

A Didangelos, X Yin, K Mandal, A Saje, A Smith… - Molecular & Cellular …, 2011 - ASBMB
Abdominal aortic aneurysms (AAA) are characterized by pathological remodeling of the
aortic extracellular matrix (ECM). However, besides the well-characterized elastolysis and …

[HTML][HTML] Aneurysm sac failure to regress after endovascular aneurysm repair is associated with lower long-term survival

TFX O'Donnell, SE Deery, LT Boitano… - Journal of Vascular …, 2019 - Elsevier
Background The early survival advantage of endovascular aneurysm repair (EVAR)
compared with open repair reverses over time, possibly because of higher rates of …

The role of prostaglandin E2 in human vascular inflammation

I Gomez, N Foudi, D Longrois, X Norel - Prostaglandins, Leukotrienes and …, 2013 - Elsevier
Prostaglandins (PG) are the product of a cascade of enzymes such as cyclooxygenases and
PG synthases. Among PG, PGE 2 is produced by 3 isoforms of PGE synthase (PGES) and …