Quinolones: mechanism, lethality and their contributions to antibiotic resistance

NG Bush, I Diez-Santos, LR Abbott, A Maxwell - Molecules, 2020 - mdpi.com
Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times.
They have enjoyed over 30 years of clinical usage and become essential tools in the …

Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis

N Ahmad, SD Ahuja, OW Akkerman, JWC Alffenaar… - The Lancet, 2018 - thelancet.com
Background Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed
to estimate the association of treatment success and death with the use of individual drugs …

[图书][B] WHO consolidated guidelines on tuberculosis. Module 4: treatment-drug-resistant tuberculosis treatment, 2022 update

World Health Organization - 2022 - books.google.com
The WHO Consolidated Guidelines on Tuberculosis (TB), Module 4: Treatment-Drug-
Resistant Tuberculosis Treatment 2022 update informs health care professionals in Member …

Comparative effectiveness of individualized longer and standardized shorter regimens in the treatment of multidrug resistant tuberculosis in a high burden country

A Wahid, A Ghafoor, AW Khan, YM Al-Worafi… - Frontiers in …, 2022 - frontiersin.org
Objective: To compare the effectiveness of second line injectables containing shorter
(duration 9–12 months) and longer treatment regimens (LTR, duration≥ 20 months) among …

[图书][B] WHO consolidated guidelines on drug-resistant tuberculosis treatment

World Health Organization - 2019 - apps.who.int
Executive summary Tuberculosis (TB) strains with drug resistance (DR-TB) are more difficult
to treat than drug-susceptible ones, and threaten global progress towards the targets set by …

Treatment of drug-resistant tuberculosis. An official ATS/CDC/ERS/IDSA clinical practice guideline

P Nahid, SR Mase, GB Migliori, G Sotgiu… - American journal of …, 2019 - atsjournals.org
Background: The American Thoracic Society, US Centers for Disease Control and
Prevention, European Respiratory Society, and Infectious Diseases Society of America …

The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

K Dheda, T Gumbo, G Maartens, KE Dooley… - The lancet Respiratory …, 2017 - thelancet.com
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …

[图书][B] WHO treatment guidelines for drug-resistant tuberculosis

World Health Organization - 2016 - apps.who.int
The WHO treatment guidelines for drug-resistant tuberculosis, 2016 update aims to support
health professionals worldwide to respond to the continued challenge posed by …

Building a tuberculosis-free world: The Lancet Commission on tuberculosis

MJA Reid, N Arinaminpathy, A Bloom, BR Bloom… - The Lancet, 2019 - thelancet.com
Executive summary Tuberculosis can be treated, prevented, and cured. Rapid, sustained
declines in tuberculosis deaths in many countries during the past 50 years provide …

Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis

Z Lan, N Ahmad, P Baghaei, L Barkane… - The Lancet …, 2020 - thelancet.com
Background Treatment of multidrug-resistant tuberculosis requires long-term therapy with a
combination of multiple second-line drugs. These drugs are associated with numerous …