Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which
is of great significance to tissue development. ECM in muscle fiber niche consists of three …

Skeletal muscle extracellular matrix (ECM) is critical for muscle force production and the
regulation of important physiological processes during growth, regeneration, and …

Volumetric muscle loss (VML) is a loss of over∼ 10% of muscle mass that results in
functional impairment. Although skeletal muscle possesses the ability to repair and …

Skeletal muscle is endowed with a remarkable capacity for regeneration, primarily due to the
reserve pool of muscle resident satellite cells. The satellite cell is the physiologically …

Volumetric muscle loss (VML) is the surgical or traumatic loss of skeletal muscle, which can
cause loss of limb function or permanent disability. VML injuries overwhelms the …

Abstract Laminin (LM)-111 supplementation has improved muscle regeneration in several
models of disease and injury. This study investigated a novel hydrogel composed of …

Minced muscle autografting mediates de novo myofiber regeneration and promotes partial
recovery of neuromuscular strength after volumetric muscle loss injury (VML). A major …

Volumetric muscle loss (VML) is traumatic or surgical loss of skeletal muscle with resultant
functional impairment. Skeletal muscle's innate capacity for regeneration is lost with VML …

Satellite cells function as precursor cells in mature skeletal muscle homeostasis and
regeneration. In healthy tissue, these cells are maintained in a state of quiescence by a …

Laminin-111 protein complex links the extracellular matrix to integrin α7β1 in sarcolemma,
thus replacing in dystrophic muscles links normally insured by the dystrophin complex …