The role and importance of mechanical properties of cells and tissues in cellular function,
development and disease has widely been acknowledged, however standard techniques …

Many important biological functions and processes are reflected in cell and tissue
mechanical properties such as elasticity and viscosity. However, current techniques used for …

Brillouin spectroscopy and imaging are emerging techniques in analytical science,
biophotonics, and biomedicine. They are based on Brillouin light scattering from acoustic …

The genetic elements required to tune gene expression are partitioned in active and
repressive nuclear condensates. Chromatin compartments include transcriptional clusters …

TAR DNA-binding protein of 43 kDa (TDP-43) and fused in sarcoma (FUS) are RNA binding
proteins (RBPs) primarily located in the nucleus, and involved in numerous aspects of RNA …

Immune checkpoint inhibitor therapy has changed clinical practice for patients with different
cancers, since these agents have demonstrated a significant improvement of overall survival …

Several techniques have been developed over the past few decades to assess the
mechanical properties of biological samples, which has fueled a rapid growth in the fields of …

Many problems in mechanobiology urgently require characterization of the micromechanical
properties of cells and tissues. Brillouin light scattering has been proposed as an emerging …

Quantitative measurements of physical parameters become increasingly important for
understanding biological processes. Brillouin microscopy (BM) has recently emerged as one …

In this work, we quantify the mechanical properties of the extra-cellular matrix (ECM) in live
zebrafish using Brillouin microscopy. Optimization of the imaging conditions and …