Preclinical in vivo-models to investigate HIPEC; current methodologies and challenges

RF Helderman, DR Löke, PJ Tanis, JB Tuynman… - Cancers, 2021 - mdpi.com
Simple Summary Efficacy of cytoreductive surgery (CRS) combined with hyperthermic
intraperitoneal chemotherapy (HIPEC) depends on patient selection, tumor type, delivery …

[HTML][HTML] Topical administration of pterostilbene accelerates burn wound healing in diabetes through activation of the HIF1α signaling pathway

W Hu, H Yu, X Zhou, M Li, L Xiao, Q Ruan, X Huang… - Burns, 2022 - Elsevier
Impaired wound healing is one of a variety of severe diabetic complications and involves
many factors, including consistent oxidative stress, prolonged inflammation, impaired …

[HTML][HTML] Experimental models of high-risk bowel anastomosis in rats: A systematic review

G Ntampakis, MG Pramateftakis… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Anastomotic leaks remain one of the most dreaded complications in
gastrointestinal surgery causing significant morbidity, that negatively affect the patients' …

The influence of platelet-rich plasma (PRP) on colonic anastomosis healing impaired by intraperitoneal 5-flourouracil application. An experimental study

M Gorur, A Sozutek, O Irkorucu… - Acta Cirúrgica Brasileira, 2020 - SciELO Brasil
Abstract Purpose 5-flourourasil (5-FU) is commonly used for early intraperitoneal
chemotherapy in colorectal or appendiceal cancer patients with peritoneal carcinomatosis …

[HTML][HTML] Platelet rich plasma effectiveness in bowel anastomoses: A systematic review

G Geropoulos, K Psarras, D Giannis… - World Journal of …, 2021 - ncbi.nlm.nih.gov
BACKGROUND Anastomotic leak constitutes a major problem in abdominal surgery.
Technical insufficiency, topical or systemic factors contribute to disrupted healing of the …

Comparison of Platelet‐Rich Plasma‐Impregnated Suture Material with Low and High Platelet Concentration to Improve Colonic Anastomotic Wound Healing in Rats

MA Aydin, EM Guler, AS Demiroz… - Gastroenterology …, 2020 - Wiley Online Library
Objective. This study was designed to investigate the impact of using suture material
impregnated with platelet‐rich plasma (PRP) in different platelet concentrations on colonic …

Effect of platelet‐rich plasma on colon anastomosis in rats in which hyperthermic intra‐peritoneal chemotherapy was performed using 5‐fluorouracil

M Göksu, H Alakuş, S Ertan, S Akgün - ANZ Journal of Surgery, 2020 - Wiley Online Library
Background Hyperthermic intra‐peritoneal chemotherapy (HIPEC) performed in patients
with peritoneal carcinomatosis has a cytotoxic effect on tumour cells. This cytotoxic effect …

The healing effects of prp and thymoquinone on dss induced inflammatory bowel disease in rats

H Ozden, G Karaca - 2021 - annalsmedres.org
Aim: Crohn's disease and ulcerative colitis are included in inflammatory bowel disease
(IBD). The study aimed to compare the healing effects of two promising therapeutic agents …

[HTML][HTML] Platelet-rich plasma in surgical practice: a review

SV Minaev, SI Timofeev, AN Grigorova… - Russian Journal of …, 2023 - rps-journal.ru
The use of platelet-rich plasma (PRP) in clinical settings is a current issue in various fields of
medicine. There is no unified and structured approach to PRP preparation and application …

[引用][C] Обогащенная тромбоцитарная плазма в хирургической практике. Обзор литературы

СВ Минаев, СИ Тимофеев, АН Григорова… - Российский вестник …, 2023 - rps-journal.ru