The cingulum bundle is a prominent white matter tract that interconnects frontal, parietal, and
medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus. Despite its …

The posterior cingulate cortex is a highly connected and metabolically active brain region.
Recent studies suggest it has an important cognitive role, although there is no consensus …

There has been much recent interest in using magnetic resonance diffusion imaging to
provide information about anatomical connectivity in the brain, by measuring the anisotropic …

We have developed a method for automated probabilistic reconstruction of a set of major
white-matter pathways from diffusion-weighted MR images. Our method is called TRACULA …

The disconnection hypothesis suggests that the core symptoms of schizophrenia (SZ) are
related to aberrant, or 'dys-', connectivity between distinct brain regions. A proliferation of …

While multiple theories have been put forth regarding the origin of schizophrenia, by far the
vast majority of evidence points to the neurodevelopmental model in which developmental …

Unlike neurologic conditions, such as brain tumors, dementia, and stroke, the neural
mechanisms for all psychiatric disorders remain unclear. A large body of research obtained …

Understanding the large-scale structural network formed by neurons is a major challenge in
system neuroscience. A detailed connectivity map covering the entire brain would therefore …

Both post-mortem and neuroimaging studies have contributed significantly to what we know
about the brain and schizophrenia. MRI studies of volumetric reduction in several brain …

In patients with schizophrenia neuroimaging studies have revealed global differences with
some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion …