Influenza virus neuraminidase structure and functions

JL McAuley, BP Gilbertson, S Trifkovic… - Frontiers in …, 2019 - frontiersin.org
With the constant threat of emergence of a novel influenza virus pandemic, there must be
continued evaluation of the molecular mechanisms that contribute to virulence. Although the …

Nanotherapeutics for nose-to-brain drug delivery: an approach to bypass the blood brain barrier

D Lee, T Minko - Pharmaceutics, 2021 - mdpi.com
Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

[HTML][HTML] Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

V Bourganis, O Kammona, A Alexopoulos… - European Journal of …, 2018 - Elsevier
Central nervous system (CNS) disorders (eg, multiple sclerosis, Alzheimer's disease, etc.)
represent a growing public health issue, primarily due to the increased life expectancy and …

Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase

M Cohen, XQ Zhang, HP Senaati, HW Chen, NM Varki… - Virology journal, 2013 - Springer
Abstract Background Influenza A virus (IAV) neuraminidase (NA) cleaves sialic acids (Sias)
from glycans. Inhibiting NA with oseltamivir suppresses both viral infection, and viral release …

Moisture-associated skin damage: overview and pathophysiology

M Gray, JM Black, MM Baharestani… - Journal of Wound …, 2011 - journals.lww.com
Moisture-associated skin damage (MASD) is caused by prolonged exposure to various
sources of moisture, including urine or stool, perspiration, wound exudate, mucus, saliva …

Propulsion in a viscoelastic fluid

E Lauga - Physics of Fluids, 2007 - pubs.aip.org
Flagella beating in complex fluids are significantly influenced by viscoelastic stresses.
Relevant examples include the ciliary transport of respiratory airway mucus and the motion …

Cellular and molecular biology of airway mucins

EP Lillehoj, K Kato, W Lu, KC Kim - … review of cell and molecular biology, 2013 - Elsevier
Airway mucus constitutes a thin layer of airway surface liquid with component
macromolecules that covers the luminal surface of the respiratory tract. The major function of …

Ventilator-associated pneumonia: a review

KA Davis - Journal of Intensive Care Medicine, 2006 - journals.sagepub.com
Ventilator-associated pneumonia is the most frequent intensive care unit (ICU)-related
infection in patients requiring mechanical ventilation. In contrast to other ICU-related …

A beneficiary role for neuraminidase in influenza virus penetration through the respiratory mucus

X Yang, L Steukers, K Forier, R Xiong, K Braeckmans… - PloS one, 2014 - journals.plos.org
Swine influenza virus (SIV) has a strong tropism for pig respiratory mucosa, which consists
of a mucus layer, epithelium, basement membrane and lamina propria. Sialic acids present …

[PDF][PDF] Probiotics, immunity and exercise: a review

NP West, DB Pyne, JM Peake, AW Cripps - Exerc Immunol Rev, 2009 - eir-isei.de
Nutritional practices that promote good health and optimal athletic performance are of
interest to athletes, coaches, exercise scientists and dietitians. Probiotic supplements …