[HTML][HTML] Macrophage activation and its role in repair and pathology after spinal cord injury

JC Gensel, B Zhang - Brain research, 2015 - Elsevier
The injured spinal cord does not heal properly. In contrast, tissue repair and functional
recovery occur after skin or muscle injuries. The reason for this dichotomy in wound repair is …

Are reactive oxygen species always detrimental to pathogens?

CN Paiva, MT Bozza - Antioxidants & redox signaling, 2014 - liebertpub.com
Reactive oxygen species (ROS) are deadly weapons used by phagocytes and other cell
types, such as lung epithelial cells, against pathogens. ROS can kill pathogens directly by …

Cutaneous manifestations of human and murine leishmaniasis

BM Scorza, EM Carvalho, ME Wilson - International journal of molecular …, 2017 - mdpi.com
The leishmaniases are diseases caused by pathogenic protozoan parasites of the genus
Leishmania. Infections are initiated when a sand fly vector inoculates Leishmania parasites …

Immune responses in leishmaniasis: An overview

AC Costa-da-Silva, DO Nascimento… - Tropical medicine and …, 2022 - mdpi.com
Leishmaniasis is a parasitic, widespread, and neglected disease that affects more than 90
countries in the world. More than 20 Leishmania species cause different forms of …

Redox control of inflammation in macrophages

B Brüne, N Dehne, N Grossmann, M Jung… - Antioxidants & redox …, 2013 - liebertpub.com
Macrophages are present throughout the human body, constitute important immune effector
cells, and have variable roles in a great number of pathological, but also physiological …

A comprehensive review of chalcone derivatives as antileishmanial agents

MVP de Mello, B de Azevedo Abrahim-Vieira… - European Journal of …, 2018 - Elsevier
Leishmaniasis is a group of infectious neglected tropical diseases caused by more than 20
pathogenic species of Leishmania sp. Due to the limitations of the current treatments …

Insights into the sand fly saliva: Blood-feeding and immune interactions between sand flies, hosts, and Leishmania

T Lestinova, I Rohousova, M Sima… - PLoS neglected …, 2017 - journals.plos.org
Background Leishmaniases are parasitic diseases present worldwide that are transmitted to
the vertebrate host by the bite of an infected sand fly during a blood feeding. Phlebotomine …

Current status on prevention and treatment of canine leishmaniasis

RM Reguera, M Moran, Y Perez-Pertejo… - Veterinary …, 2016 - Elsevier
Canine leishmaniasis (CanL) is a parasite-borne disease mainly induced by Leishmania
infantum in the Old World and Leishmania chagasi (infantum) in the New World. CanL is a …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

[PDF][PDF] The C-type lectin receptors dectin-1, MR, and SIGNR3 contribute both positively and negatively to the macrophage response to Leishmania infantum

L Lefèvre, G Lugo-Villarino, E Meunier, A Valentin… - Immunity, 2013 - cell.com
Macrophages act as the primary effector cells during Leishmania infection through
production of reactive oxygen species (ROS) and interleukin-1β (IL-1β). However, how …